Results 21 to 30 of about 353,813 (260)

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

A Concept Crystal Habit Phase Diagram and Data for Curcumin in Isopropanol: Classical Versus Non-Classical Crystallization

Crystals
Cooling crystallization experiments of curcumin in isopropanol confirmed that curcumin can crystallize via classical or nonclassical pathways, depending on the levels of supersaturation and supercooling.
Mahmoud Ranjbar, Mayank Vashishtha, Gavin Walker, K. Vasanth Kumar   +3 more
doaj   +1 more source

Low Temperature Area Selective Atomic Layer Deposition of Ruthenium Dioxide Thin Films Using Polymers as Inhibition Layers

Advanced Materials Interfaces, 2023
Area selective atomic layer deposition (AS‐ALD) is an interesting bottom‐up approach due to its self‐aligned fabrication potential. Ruthenium dioxide (RuO2) is an important material for several applications, including microelectronics, demanding area ...
Nithin Poonkottil, Hannes Rijckaert, Khannan Rajendran, Robin R. Petit, Lisa I. D. J. Martin, Dries Van Thourhout, Isabel Van Driessche, Christophe Detavernier, Jolien Dendooven   +8 more
doaj   +1 more source

Green and environmental friendly synthesis of copper (II) and nickel (II) complexes of rhodanine and its antibacterial effectiveness

Current Research in Green and Sustainable Chemistry, 2022
This study present the solid state synthesis of Copper (II) and Nickel (II) Complexes of Rhodanine with molecular formula [Cu(HRD)2(CH3COO)2] represented as 1a and [Ni(HRD)2(NO3)2] (HRD = C3H3NOS2) represented as 2a. It was synthesized by mechanochemical
Samuel A. Ajala, Adedibu Clement Tella, Idowu Olatunbosun Adeoye, Ojeyemi Matthew Olabemiwo, Babawale Emmanuel Abiola, Sunday Adewale Akintelu   +5 more
doaj   +1 more source

ASSIST: Refinement of a Benefits Navigator Intervention Among Low‐Income Pediatric Oncology Families

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Children with cancer living in poverty experience worse survival and quality of life. Interventions connecting low‐income families to benefits (e.g., Supplemental Nutrition Assistance Program [SNAP] improve health outcomes; yet nearly 50% of SNAP‐eligible pediatric oncology families are unenrolled.
Puja J. Umaretiya, Selena Murcia Mendez, Jennifer Kellett, Sarah Wright, Marisel Ponton, Robin T. Higashi, Rahela Aziz‐Bose, Colleen A. Kelly, Ayesha Zia, Joanne Wolfe, Sandi L. Pruitt, Kira Bona   +11 more
wiley   +1 more source

Process Analytical Technology Obtained Metastable Zone Width, Nucleation Rate and Solubility of Paracetamol in Isopropanol—Theoretical Analysis

Pharmaceuticals
Background: Metastable zone width (MSZW) and solubility are crucial for developing crystallization procedures in the purification of active pharmaceutical ingredients (APIs).
Mahmoud Ranjbar, Mayank Vashishtha, Gavin Walker, K. Vasanth Kumar   +3 more
doaj   +1 more source

Time to Diagnosis Among Children and Adolescents With Cancer in Québec, Canada: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen, Ronald D. Barr, Erin Strumpf, Mariam El‐Zein, Eduardo L. Franco, Talía Malagón   +5 more
wiley   +1 more source

Designing Continuous Crystallization Protocols for Curcumin Using PAT Obtained Batch Kinetics

Crystals
Developing theory-informed standard operating procedures (SOPs) for the continuous crystallisation of pharmaceuticals still remains a bottleneck. For the continuous manufacturing of pharmaceuticals, the current methods rely on the laborious trial-and ...
Mayank Vashishtha, Mahmoud Ranjbar, Gavin Walker, K. Vasanth Kumar   +3 more
doaj   +1 more source

A Novel Family of Triangular Co^II₂Ln^III and Co^II₂Y^III Clusters by the Employment of Di-2-Pyridyl Ketone

Magnetochemistry, 2019
The synthesis, structural characterization and magnetic study of novel CoII/4f and CoII/YIII clusters are described. In particular, the initial employment of di-2-pyridyl ketone, (py)2CO, in mixed metal Co/4f chemistry, provided access to four triangular
Constantinos G. Efthymiou, Áine Ní Fhuaráin, Júlia Mayans, Anastasios Tasiopoulos, Spyros P. Perlepes, Constantina Papatriantafyllopoulou   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source