Results 11 to 20 of about 71,435 (301)
A Stepwise Framework for the Systematic Development of Lipid Nanoparticles
Biomolecules, 2022 A properly designed nanosystem aims to deliver an optimized concentration of the active pharmaceutical ingredient (API) at the site of action, resulting in a therapeutic response with reduced adverse effects.
João Basso +7 more
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Pharmaceutics, 2021 Gastrointestinal absorption remains indispensable in the systemic delivery of most drugs, even though it presents several challenges that, paradoxically, may also provide opportunities that can be exploited to achieve maximal bioavailability.
Sui Ling Janet Tan, Nashiru Billa
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Multifunctional nanocarriers for lung drug delivery [PDF]
, 2020 Nanocarriers have been increasingly proposed for lung drug delivery applications. The strategy of combining the intrinsic and more general advantages of the nanostructures with specificities that improve the therapeutic outcomes of particular clinical ...
Grenha, Ana, Pontes, Jorge Filipe
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Lipid-Based Nanocarriers for Ophthalmic Administration: Towards Experimental Design Implementation
Pharmaceutics, 2021 Nanotherapeutics based on biocompatible lipid matrices allow for enhanced solubility of poorly soluble compounds in the treatment of ophthalmic diseases, overcoming the anatomical and physiological barriers present in the eye, which, despite the ease of ...
Felipe M. González-Fernández +4 more
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Optimization of the Conditions of Solid Lipid Nanoparticles (SLN) Synthesis
Molecules, 2022 Solid lipid nanoparticles (SLNs) have been synthesized as potential drug delivery systems. They are classified as solid lipid nanocarriers that can successfully carry both hydrophilic and hydrophobic drugs.
Ewelina Musielak +2 more
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Development of Solid Lipid Nanoparticles for Controlled Amiodarone Delivery
Methods and Protocols, 2023 In various drug delivery systems, solid lipid nanoparticles are dominantly lipid-based nanocarriers. Amiodarone hydrochloride is an antiarrhythmic agent used to treat severe rhythm disturbances.
Andreea Creteanu +5 more
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Nanoparticles in the treatment of chronic lung diseases [PDF]
, 2019 Nanoparticles, although considered a topic of modern medicine, actually have an interesting history. Currently, advances in nanomedicine hold great promise as drug carrier systems for sustained release and targeted delivery of diverse therapeutic agents.
Alexescu, Teodora G +9 more
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Native silica nanoparticles are powerful membrane disruptors [PDF]
, 2015 Silica nanoparticles are under development for intracellular drug delivery applications but can also have cytotoxic effects including cell membrane damage.
Alkhammash, Hend I. +3 more
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Lipid Nanoparticles for Ocular Gene Delivery
Journal of Functional Biomaterials, 2015 Lipids contain hydrocarbons and are the building blocks of cells. Lipids can naturally form themselves into nano-films and nano-structures, micelles, reverse micelles, and liposomes.
Yuhong Wang +2 more
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Cancer Nanotechnology, 2023 Myricetin is a flavonoid with anticancer properties. This study aimed to formulate myricetin in the form of solid lipid nanoparticles (SLN), decorated with chitosan (CS) and active-targeted with folic acid (FA).
Niloufar Khatamian +4 more
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