Results 1 to 10 of about 114,317 (238)

Solid Lipid Nanoparticles

Encyclopedia, 2022
Solid lipid nanoparticles (SLNs) are produced from physiologically biocompatible lipids. They have been proven to improve solubility, cellular uptake, and stability, reduce enzyme degradation, and prolong the circulation time of various drugs. SLNs have been applied in the oral, parenteral, transdermal, intranasal, ocular, and pulmonary drug delivery ...
Thi-Thao-Linh Nguyen, Van-An Duong
doaj   +4 more sources

Solid lipid nanoparticles in pancreatic cancer treatment [PDF]

BJC Reports
Pancreatic cancer comes with one of the poorest prognoses of all cancers and as such it is crucial that new therapies are developed to improve on the current statistics.
Mia Dunn, Lewis Dymock, Clare Hoskins
doaj   +2 more sources

Solid Lipid Nanoparticles (SLN): Formulation and Fabrication

Pharmaceutical Sciences and Research, 2023
Solid lipid nanoparticles (SLN) have emerged as a novel drug delivery system and have been utilized for delivering various kinds of drugs since the 1990s. These particles may consist of multiple solid lipids, including glycerides, waxes, and fatty acids,
Gabriella F. Punu, Yahdiana Harahap, Qonita Kurnia Anjani, Pietradewi Hartrianti, Ryan F. Donnelly, Delly Ramadon   +5 more
doaj   +1 more source

Novel sulpiride-loaded solid lipid nanoparticles with enhanced intestinal permeability

International Journal of Nanomedicine, 2013
Waheed M Ibrahim,1 Abdullah H AlOmrani,2 Alaa Eldeen B Yassin31Drug Sector, Saudi Food and Drug Authority, 2Department of Pharmaceutics, College of Pharmacy, King Saud University, 3Department of Pharmaceutical Sciences, College of Pharmacy, King Saud bin
Ibrahim WM, AlOmrani AH, Yassin AE
openalex   +2 more sources

Resveratrol-Loaded Solid Lipid Nanoparticles Reinforced Hyaluronic Hydrogel: Multitarget Strategy for the Treatment of Diabetes-Related Periodontitis [PDF]

Biomedicines
Raffaele Conte, Anna Valentino, Fabrizia Sepe, Francesco Gianfreda, Roberta Condò, Loredana Cerroni, Anna Calarco, Gianfranco Peluso   +7 more
openalex   +2 more sources

Solid Lipid Nanoparticles vs. Nanostructured Lipid Carriers: A Comparative Review

Pharmaceutics, 2023
Solid–lipid nanoparticles and nanostructured lipid carriers are delivery systems for the delivery of drugs and other bioactives used in diagnosis, therapy, and treatment procedures. These nanocarriers may enhance the solubility and permeability of drugs,
Cláudia Viegas, Ana B. Patrício, João M. Prata, Akhtar Nadhman, Pavan Kumar Chintamaneni, Pedro Fonte   +5 more
doaj   +1 more source

Central Composite Design for Formulation and Optimization of Solid Lipid Nanoparticles to Enhance Oral Bioavailability of Acyclovir

Molecules, 2021
Treatment of herpes simplex infection requires high and frequent doses of oral acyclovir to attain its maximum therapeutic effect. The current therapeutic regimen of acyclovir is known to cause unwarranted dose-related adverse effects, including acute ...
Haniza Hassan, Siti Khadijah Adam, Ekram Alias, Meor Mohd Redzuan Meor Mohd Affandi, Ahmad Fuad Shamsuddin, Rusliza Basir   +5 more
doaj   +1 more source

Ultrasmall Solid-Lipid Nanoparticles via the Polysorbate Sorbitan Phase-Inversion Temperature Technique: A Promising Vehicle for Antioxidant Delivery into the Skin

Pharmaceutics, 2023
Solid lipid nanoparticles promote skin hydration via stratum corneum occlusion, which prevents water loss by evaporation, and via the reinforcement of the skin’s lipid-film barrier, which occurs through the adhesion of the nanoparticles to the stratum ...
Francesca Della Sala, Assunta Borzacchiello, Chiara Dianzani, Elisabetta Muntoni, Monica Argenziano, Maria Teresa Capucchio, Maria Carmen Valsania, Annalisa Bozza, Sara Garelli, Maria Di Muro, Franco Scorziello, Luigi Battaglia   +11 more
doaj   +1 more source

Preclinical Evaluation of Lipid-Based Nanosystems

Pharmaceutics, 2021
The use of lipid-based nanosystems, including lipid nanoparticles (solid lipid nanoparticles—SLN, and nanostructured lipid carriers—NLC), nanoemulsions, and liposomes, among others, is widespread [...]
Ana Catarina Silva, José Manuel Sousa Lobo   +1 more
doaj   +1 more source

Lipid Nanoparticles Functionalized with Antibodies for Anticancer Drug Therapy

Pharmaceutics, 2023
Nanotechnology takes the lead in providing new therapeutic options for cancer patients. In the last decades, lipid-based nanoparticles—solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), liposomes, and lipid–polymer hybrid ...
Ana Camila Marques, Paulo C. Costa, Sérgia Velho, Maria Helena Amaral   +3 more
doaj   +1 more source