Results 21 to 30 of about 114,436 (357)
Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]
, 2020 Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui +3 more
core +2 more sources
A correlative model to predict in vivo AUC for nanosystem drug delivery with release rate-limited absorption [PDF]
, 2012 Purpose. Drug release from nanosystems at the sites of either absorption or effect biophase is a major determinant of its biological action. Thus, in vitro drug release is of paramount importance in gaining insight for the systems performance in vivo ...
Adibkia, Khosro +6 more
core +3 more sources
Use of Microfluidics to Prepare Lipid-Based Nanocarriers
Pharmaceutics, 2023 Lipid-based nanoparticles (LBNPs) are an important tool for the delivery of a diverse set of drug cargoes, including small molecules, oligonucleotides, and proteins and peptides. Despite their development over the past several decades, this technology is
Alicia Vogelaar +4 more
doaj +1 more source
Nanoparticles in the treatment of chronic lung diseases [PDF]
, 2019 Nanoparticles, although considered a topic of modern medicine, actually have an interesting history. Currently, advances in nanomedicine hold great promise as drug carrier systems for sustained release and targeted delivery of diverse therapeutic agents.
Alexescu, Teodora G +9 more
core +2 more sources
Lipid Nanoparticles for the Posterior Eye Segment
Pharmaceutics, 2021 This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for pathologies affecting the posterior ocular segment. Eye anatomy and the most
Lorena Bonilla +8 more
doaj +1 more source
Preparation of Nanoparticles of Digoxin Solid Lipid
Chemical Engineering Transactions, 2017 In order to prove the role of solid lipid nanoparticles in oral absorption and bioavailability, the biodegradable monoglyceride with low toxicity and good biocompatibility is used as lipid materials to prepare nanoparticles of digoxin solid lipid and ...
Ping Luo, Yangwu Liu
doaj +1 more source
Innovative Agents for Actinic Keratosis and Nanocarriers Enhancing Skin Penetration [PDF]
, 2010 Actinic keratosis and cutaneous squamous cell carcinoma are of increasing importance with aging and increased ultraviolet light exposure in Western societies. Efficient and well-tolerated therapy is still a matter of concern.
Höltje, H.-D. +3 more
core +1 more source
Solid lipid nanoparticles from amphiphilic calixpyrroles [PDF]
Journal of Colloid and Interface Science, 2016 Macrocyclic amphiphiles form interesting self-assembling structures, including solid lipid nanoparticles, which have potential applications in drug encapsulation. Aryl-extended calixpyrroles, which act as anion binding hosts, are expected to form solid lipid nanoparticles, even though the alkyl chains have unusual perpendicular geometry with respect to
Galán, Albano +4 more
openaire +5 more sources
Saudi Pharmaceutical Journal, 2020 The aim of these studies was to determine the miscibility of different API with lipid excipients to predict drug loading and encapsulation properties for the production of solid lipid nanoparticles and nanostructured lipid carriers.
Pedzisai A. Makoni +4 more
doaj +1 more source
Native silica nanoparticles are powerful membrane disruptors [PDF]
, 2015 Silica nanoparticles are under development for intracellular drug delivery applications but can also have cytotoxic effects including cell membrane damage.
Alkhammash, Hend I. +3 more
core +1 more source