Results 41 to 50 of about 5,632,475 (303)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Nature of organic carbon and nitrogen in physically protected organic matter of some Australian soils as revealed by solid-state 13 C and 15 N NMR spectroscopy [PDF]

open access: yesAustralian Journal of Soil Research, 2000
The <53-□m particle-size fractions of 5 different Australian soils were subjected to high energy ultraviolet (UV) photo-oxidation for a period of 2 h in order to remove most of the physically unprotected organic material. Solid-state 13C and 15N nuclear magnetic resonance (NMR) spectroscopy was applied for characterising the chemical nature of ...
Knicker, Heike, Skjemstad, J. O.
openaire   +2 more sources

Honorary issue dedicated to the 80th anniversary of Professor Ihor Stasyuk [PDF]

open access: yes, 2018
This special issue of the "Condensed Matter Physics" journal is dedicated to Professor Ihor Stasyuk, a prominent scientist and lecturer who celebrates his 80th birthday on September 23, 2018. The articles in this collections represent different fields of
J.K. Freericks   +3 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Unusual lattice vibration characteristics in whiskers of the pseudo-one-dimensional titanium trisulfide TiS3

open access: yesNature Communications, 2016
Transition metal trichalcogenides are layered materials with strong in-plane anisotropy, and their vibrational characteristics remain largely unexplored.
Kedi Wu   +10 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Room-temperature terahertz anomalous Hall effect in Weyl antiferromagnet Mn3Sn thin films

open access: yesNature Communications, 2020
Antiferromagnets promise great potential for spintronic applications due to their spin excitations at terahertz frequencies, however, read out of the spin state is hindered by the small response to external fields.
Takuya Matsuda   +5 more
doaj   +1 more source

Dynamic electron correlations with charge order wavelength along all directions in the copper oxide plane

open access: yesNature Communications, 2021
Knowledge of effective Coulomb interactions is central to understand emergent quantum phases in strongly correlated systems. Here, Boschini et al.
F. Boschini   +20 more
doaj   +1 more source

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