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Excipient Stability in Oral Solid Dosage Forms: A Review
AAPS PharmSciTech, 2017The choice of excipients constitutes a major part of preformulation and formulation studies during the preparation of pharmaceutical dosage forms. The physical, mechanical, and chemical properties of excipients affect various formulation parameters, such as disintegration, dissolution, and shelf life, and significantly influence the final product ...
Michael A Repka +2 more
exaly +3 more sources
Use of similarity scoring in the development of oral solid dosage forms
International Journal of Pharmaceutics, 2016In the oral solid dosage form space, material physical properties have a strong impact on the behaviour of the formulation during processing. The ability to identify materials with similar characteristics (and thus expected to exhibit similar behaviour) within the company's portfolio can help accelerate drug development by enabling early assessment and
Dolapo Olusanmi +2 more
exaly +3 more sources
New oral solid dosage form for furosemide oral administration
European Journal of Pharmaceutics and Biopharmaceutics, 2012Furosemide (FURO) is a drug labeled in class IV of the Biopharmaceutics Classification System (BCS) as it is both poor soluble and poor permeable. The aim of this work was to improve FURO biopharmaceutical properties by its formulation in a new solid oral dosage form.
Luana, Perioli +2 more
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The automation of dissolution testing of solid oral dosage forms
Journal of Pharmaceutical and Biomedical Analysis, 1992Dissolution testing of solid oral dosage forms plays a very important part both in the development of new products and in quality control. A fully automated system for dissolution testing known as AUTO DISS is presented and its components are described.
E, Lamparter, C H, Lunkenheimer
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Current formulation approaches in design and development of solid oral dosage forms through three-dimensional printing [PDF]
Progress in Additive Manufacturing, 2020 Three-dimensional (3D) printing technologies are continuously applied to novel fields, laying the foundations for a new industrial revolution. With regard to pharmaceutical sciences, 3D printed drug products are emerging as attractive and innovative ...
Carlo Curti +2 more
exaly +3 more sources
Stability of pharmaceutical salts in solid oral dosage forms
Drug Development and Industrial Pharmacy, 2017Using pharmaceutical salts in solid dosage forms can raise stability concerns, especially salt dissociation which can adversely affect the product performance. Therefore, a thorough understanding of the salt instability encountered in solid-state formulations is imperative to ensure the product quality.
Haichen, Nie +2 more
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Professional nurse (London, England), 1993
The oral route of drug administration is the most convenient for patients, with tablets emerging as the most popular solid oral dosage form used today. Standard compressed, controlled-release and coated tablets are the most common form of solid oral dosages. A wide range and diversity of ingredients are often included in tablet formulations.
M, Helliwell, D, Taylor
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The oral route of drug administration is the most convenient for patients, with tablets emerging as the most popular solid oral dosage form used today. Standard compressed, controlled-release and coated tablets are the most common form of solid oral dosages. A wide range and diversity of ingredients are often included in tablet formulations.
M, Helliwell, D, Taylor
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2015
In the last 25 to 30 years, a huge resource in both academia and industry has been devoted to the development of drug delivery systems that target drugs more effectively to their therapeutic site. Much of this work has been successful, and is reported in this text.
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In the last 25 to 30 years, a huge resource in both academia and industry has been devoted to the development of drug delivery systems that target drugs more effectively to their therapeutic site. Much of this work has been successful, and is reported in this text.
openaire +1 more source
Bioequivalency of solid oral dosage forms of cefixime
International Journal of Pharmaceutics, 1988Abstract A study was performed in 24 healthy subjects to determine whether tablet and capsule formulations of cefixime (CL 284,635; FK027), a new oral cephalosporin, given as a single 400 mg dose, were bioequivalent to one another and to a reference oral solution.
Robert D. Faulkner +6 more
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