Results 81 to 90 of about 913,823 (355)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Developments and Applications of Molecularly Imprinted Polymer-Based In-Tube Solid Phase Microextraction Technique for Efficient Sample Preparation

Molecules
Despite advancements in the sensitivity and performance of analytical instruments, sample preparation remains a bottleneck in the analytical process. Currently, solid-phase extraction is more widely used than traditional organic solvent extraction due to
Hiroyuki Kataoka, Atsushi Ishizaki, Keita Saito, Kentaro Ehara   +3 more
doaj   +1 more source

Preconcentration, determination and speciation of iron by solid-phase extraction using dimethyl (E)-2-[(Z)-1-acetyl)-2-hydroxy-1-propenyl]-2-butenedioate

Química Nova, 2012
A new sensitive and selective procedure for speciation of trace dissolved Fe(III) and Fe(II), using modified octadecyl silica membrane disks and determination by flame atomic absorption spectrometry was developed.
Gholamreza Khayatian, Shahed Hassanpoor, Farough Nasiri, Amin Zolali   +3 more
doaj   +1 more source

Weak anion-exchange hypercrosslinked sorbent in on-line solid-phase extraction-liquid chromatography coupling to achieve automated determination with an effective clean-up [PDF]

, 2010
A mixed-mode polymeric sorbent was on-line coupled to liquid chromatography (LC) for the first time and applied it to the selective solid-phase extract a group of pharmaceuticals in complex environmental water samples. The mixed-mode polymeric sorbent is
Borrull, F., Cormack, P.A.G., Fontanals, N., Marce, R.M., Sherrington, D.C.   +4 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Research Progress on Sample Pretreatment Techniques for Alternaria Toxins Residues Analysis in Food

Liang you shipin ke-ji
The food infected by Alternaria species can produce Alternaria toxins with genotoxicity, cytotoxicity, reproductive toxicity, and developmental toxicity.
GUAN Wen-bi, MA Jia-li
doaj   +1 more source

Extraction Chromatography Materials Prepared with HDEHP on Different Inorganic Supports for the Separation of Gadolinium and Terbium

Metals, 2020
Bis(2-ethylhexyl)phosphoric acid (HDEHP) is frequently used as an extractant in the separation and recovery of lanthanides by solvent extraction and extraction chromatography, where HDEHP (stationary phase) is fixed on an inert support and the mobile ...
Fabiola Monroy-Guzman, Celia del Carmen De la Cruz Barba, Edgar Jaime Salinas, Vicente Garibay-Feblés, Tobias Noel Nava Entzana   +4 more
doaj   +1 more source

Comparison of two extraction methods for ergosterol determination in vegetal feeds [PDF]

, 2007
Ergosterol is the principal sterol of fungi in which it plays an essential role in cell membrane and other cellular constituents. This sterol is considered as a good marker of fungal contamination and of mycotoxin production.
Bailly, Jean Denis, Benard, Geneviève, Guerre, Philippe, Tardieu, Didier   +3 more
core  

Good manufacturing practice production of the system A amino acid transport tracer [¹¹C]MeAIB on a commercial synthesis module [PDF]

, 2013
In this report, an automated 11C-N-methyl-α-amino- isobutyric acid production on a Tracerlab FX C Pro module is described. Bioburden to the sterile filter was minimized during solid-phase extraction formulation of the HPLC purified product by the use of ...
Dam, Johan Hygum, Någren, Kjell
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source