Results 61 to 70 of about 7,149,709 (340)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Supercritical fluid extraction of veterinary drug residues from meat [PDF]
, 1999 End of project ReportExtraction is a key step in the analysis of food samples for residues of veterinary drugs. Over the last ten years there has been increasing interest in alternatives to the use of organic solvents for sample extraction.
O'Keeffe, Mandy J., O'Keeffe, Michael
core +1 more source
Química Nova, 2012 A new sensitive and selective procedure for speciation of trace dissolved Fe(III) and Fe(II), using modified octadecyl silica membrane disks and determination by flame atomic absorption spectrometry was developed.
Gholamreza Khayatian +3 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Analysis of some B-adrenergic agonists in biological matrices after evaluation of various extraction methodologies and determination procedures [PDF]
, 1994 Biological sample clean-up procedures were evaluated for the extraction of a range of /3-agonists. Once extracted the compounds were determined by immunoassay, electrochemical techniques and supercritical fluid chromatography (SFC).
Boyd, Damien Thomas
core +1 more source
Considerações sobre o preparo de amostras contendo micropoluentes estrogênicos
Química Nova, 2012 In this work, the materials used in the recovery of estrogens from aqueous matrices by filtration and solid phase extraction were evaluated. The results showed that glass-fiber filters allow a recovery and repeatability compatible with this type of ...
Marcus Vinicius de Liz +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Acta Pharmaceutica Sinica B, 2016 Biological sample pretreatment is an important step in biological sample analysis. Due to the diversity of biological matrices, the analysis of target substances in these samples presents significant challenges to sample processing.
Jie Peng +7 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Química Nova, 2006 This paper presents an easy and practical procedure to obtain silica-based C-8 type sorbents for use in solid-phase extraction. The materials are prepared by depositing poly(methyloctylsiloxane), PMOS, on the silica support.
Sonia C. N. Queiroz +2 more
doaj +1 more source