Results 61 to 70 of about 913,823 (355)

New techniques of on-line biological sample processing and their application in the field of biopharmaceutical analysis

Acta Pharmaceutica Sinica B, 2016
Biological sample pretreatment is an important step in biological sample analysis. Due to the diversity of biological matrices, the analysis of target substances in these samples presents significant challenges to sample processing.
Jie Peng, Fang Tang, Rui Zhou, Xiang Xie, Sanwang Li, Feifan Xie, Peng Yu, Lingli Mu   +7 more
doaj   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Microsphere molecularly imprinted solid-phase extraction for diazepam analysis using itaconic acid as a monomer in propanol

Open Chemistry, 2021
Diazepam (DZP) is a benzodiazepine drug used as an anti-drug and sedative. It is often misused to induce or create euphoria in combination with other drugs (high or fly sensation) or administered alone.
Hasanah Aliya Nur, Susanti Ike, Marcellino Marcellino, Maranata Gabriella Josephine, Saputri Febrina Amelia, Pratiwi Rimadani   +5 more
doaj   +1 more source

Electrospun Nanofiber Based Solid Phase Extraction [PDF]

TrAC Trends in Analytical Chemistry, 2012
Abstract The article discusses theoretical and experimental aspects of fabricating devices and developing methods for electrospun nanofiber-based solid-phase extraction (SPE). It seeks to encourage a better understanding of the use of electrospun nanofibers as a chromatographic sorbent bed.
Chigome, Samuel, Torto, Nelson
openaire   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

The Preparation and Performance of SPE Packing of Bonded Ligand on the Surface of Nanometer Titanium Dioxide

Yankuang ceshi, 2018
At present, the solid phase extraction packing of organic ligand/nano inorganic composite material is used to separate and enrich metal ions, which has become a hot research topic in analytical chemistry.
SHEN Shu-chang, LENG Mo-han, PENG Cheng, Lü Wei-chao   +3 more
doaj   +1 more source

OligoHydrogelArray (OHA) for Parallelized Solid‐Phase Extraction of Oligonucleotides

Advanced Materials Interfaces, 2023
Immobilization of oligonucleotides on solid surfaces is an important step in many experimental workflows in biology, such as gene expression analysis, genotyping, and drug discoveries.
Michelle J. Iwohn, Maximilian Seifermann, Patrick Reiser, Julius Höpfner, Razan El Khaled El Faraj, Stefan Heißler, Anna A. Popova, Pavel A. Levkin   +7 more
doaj   +1 more source

Solid Phase Sorption of Phenols on Metals Acetylacetonates [PDF]

, 2002
The solid phase extraction properties of surface layers of Eu(III), Al(III), Fe(III), Cr(III) acetylacetonates are compared for sorption some phenols and chlorophenols.
Mikhail A. Gavrilenko, Tatyana A. Kasymova, Natalya A. Gavrilenko, Es-haghi, Alcudia-León, Shuchao, Slizhov, Faustova, Fidalgo, Huijuan, Ho, Newalkar, Ellert, Vinu, Matsumoto, Miyake   +15 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source