Results 51 to 60 of about 5,285 (214)

The Preparation and Performance of SPE Packing of Bonded Ligand on the Surface of Nanometer Titanium Dioxide

Yankuang ceshi, 2018
At present, the solid phase extraction packing of organic ligand/nano inorganic composite material is used to separate and enrich metal ions, which has become a hot research topic in analytical chemistry.
SHEN Shu-chang, LENG Mo-han, PENG Cheng, Lü Wei-chao   +3 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Microextraction and Eco-Friendly Techniques Applied to Solid Matrices Followed by Chromatographic Analysis

Separations
In this review, a 5-year overview on environmentally friendly approaches for the extraction of the most relevant organic pollutants in soil, sediment, particulate matter, and sewage sludge coupled with chromatographic analysis is reported.
Attilio Naccarato, Rosangela Elliani, Antonio Tagarelli   +2 more
doaj   +1 more source

Novos sorventes baseados em poli (metiloctilsiloxano) sobre sílica para uso em extração em fase sólida New sorbents based on poly(methyloctylsiloxane) immobilized on silica for use in solid-phase extraction

Química Nova, 2006
This paper presents an easy and practical procedure to obtain silica-based C-8 type sorbents for use in solid-phase extraction. The materials are prepared by depositing poly(methyloctylsiloxane), PMOS, on the silica support.
Sonia C. N. Queiroz, Lúcio F. C. Melo, Isabel C. S. F. Jardim   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Research Progress on Sample Pretreatment Techniques for Alternaria Toxins Residues Analysis in Food

Liang you shipin ke-ji
The food infected by Alternaria species can produce Alternaria toxins with genotoxicity, cytotoxicity, reproductive toxicity, and developmental toxicity.
GUAN Wen-bi, MA Jia-li
doaj   +1 more source

Extraction Chromatography Materials Prepared with HDEHP on Different Inorganic Supports for the Separation of Gadolinium and Terbium

Metals, 2020
Bis(2-ethylhexyl)phosphoric acid (HDEHP) is frequently used as an extractant in the separation and recovery of lanthanides by solvent extraction and extraction chromatography, where HDEHP (stationary phase) is fixed on an inert support and the mobile ...
Fabiola Monroy-Guzman, Celia del Carmen De la Cruz Barba, Edgar Jaime Salinas, Vicente Garibay-Feblés, Tobias Noel Nava Entzana   +4 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Developments and Applications of Molecularly Imprinted Polymer-Based In-Tube Solid Phase Microextraction Technique for Efficient Sample Preparation

Molecules
Despite advancements in the sensitivity and performance of analytical instruments, sample preparation remains a bottleneck in the analytical process. Currently, solid-phase extraction is more widely used than traditional organic solvent extraction due to
Hiroyuki Kataoka, Atsushi Ishizaki, Keita Saito, Kentaro Ehara   +3 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source