Results 51 to 60 of about 913,823 (355)

Simultaneous determination of natural and synthetic steroid estrogens and their conjugates in aqueous matrices by liquid chromatography / mass spectrometry [PDF]

, 2005
An analytical method for the simultaneous determination of nine free and conjugated steroid estrogens was developed with application to environmental aqueous matrices.
Bean KA, Belfroid AC, Berg FD, Bowers LD, Bowers Sanaullah LD, Choi BK, Croley TR, Desbrow C, Diaz-Cruz MS, Dray J, D’Ascenzo G, Fotsis T, Fotsis T, Gangl ET, Gentilli A, Gomes RL, Gomes RL, Gomes RL, Hogenboom AC, Huang C-H, Huang C-H, Isobe T, Ito S, Jason W. Birkett, John N. Lester, Kanda R, King R, Kuch HM, Liang HR, Mallet CR, Mark D. Scrimshaw, Mouatassim–Souali A, Rachel L. Gomes, Ranney RE, Rodgers–Gray TP, Snyder SA, Steen R, Steimer T, Tabak HH, Tang PW, Ternes TA, Ternes TA, Thomas KV, Zhang H   +43 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Analytical methodologies for the determination of pharmaceuticals and personal care products (PPCPs) in sewage sludge: A critical review [PDF]

, 2019
Producción CientíficaSeveral analytical approaches have been developed for the determination of emerging pollutants (EPs), including pharmaceuticals and personal care products (PPCPs) in environmental matrices. This paper reviews the sample preparation
Barrado Esteban, Enrique, López Serna, Rebeca, Pérez Elvira, Sara Isabel, Pérez Lemus, Nereida   +3 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Stir Bar Sorptive Extraction of Volatile Compounds in Vinegar: Validation Study and Comparison With Solid Phase Microextraction [PDF]

, 2007
Stir bar sorptive extraction was evaluated for analysing volatiles in vinegar. The procedure developed shows detection and quantitation limits, and linear ranges adequate for analysing this type of compounds. The accuracy obtained was close to 100%, with
Alves, Baltussen, Bicchi, Blanch, Buettner, Carmelo García Barroso, Demyttenaere, Durán, Edwards, Enrique Durán Guerrero, García, García-Falcón, Hayasaka, Isogai, León, Luan, Luan, Marín, Natera, Noble, Palacios, Quirós, Ramón Natera Marín, Rapp, Remedios Castro Mejías, Zalacain   +25 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Recent Advance in the Sample Pretreatments for Drug Analysis in Zebrafish

Pharmaceuticals
Zebrafish, as an emerging model organism, are widely used in in vivo pharmacodynamic and pharmacokinetic studies. Unlike direct chemical analyses that require no sample preparation, most biological samples must undergo preprocessing steps—procedures that
Ting Wang, Chuyu Wang, Mingjing Luo, Xinyu Wang, Yiwen Chen, Zhi Yang, Guang Hu, Weikang Liu   +7 more
doaj   +1 more source

Optimization of Solid Phase Microextraction Conditions for Volatile Components of Foods by Using Response Surface Methodology

Turkish Journal of Agriculture: Food Science and Technology, 2017
High vacuum steam distillation, simultaneous distillation extraction, steam distillation, purge and trap methods are used for sample preparation in volatile component analysis. Since these methods are difficult and costly to implement, these methods have
Ceyda Dadalı, Yeşim Elmacı Elmacı
doaj   +1 more source

Analysis of polyphenols in apple products [PDF]

, 2012
Polyphenols of low molecular mass in apple samples were extracted by a C 18 solid-phase column, and analysed by HPLC. This extraction method had, in general, a greater extraction ability compared with liquidÐliquid extraction using the ethyl acetate ...
Mangas, J.J. (Juan), Picinelli, A.M. (Anna), Suárez, Belén   +2 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source