Results 111 to 120 of about 532,176 (314)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Acoustic phonon softening and reduced thermal conductivity in Mg2Si1-xSnx solid solutions

, 2017
The measured thermal conductivity jph of Mg2Si1-xSnx solid solutions exhibits a dramatic decrease compared with Mg2Si and Mg2Sn. By solving the full Boltzmann equation, the significantly reduced jph was quantitatively reproduced by our calculations ...
Xu, J. T., J. T. Xu, Jiang, H. C., G. Q. Liu, H. Z. Shao, Jiang, J., B. Yu, J. Jiang, X. J. Tan, Shao, H. Z., Yu, B., Liu, G. Q., Tan, X. J., H. C. Jiang   +13 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Inhomogeneous Broadening: Symmetry of Centers and Disorder in Solid Solutions and Nanocrystals

EPJ Web of Conferences, 2015
Zero-phonon electronic transitions of Cr3+ impurity ions in solid solutions and nanocrystals are studied.
Feofilov S.P., Kaplyanskii A.A., Kulinkin A.B., Zakharchenya R.I., Ovanesyan K., Petrosyan A., Dujardin C.   +6 more
doaj   +1 more source

Chemical treatment of monocrystalline cadmium telluride and Cd1-xMnxTe solid solutions by H2O2 – HI – citratic acid etchant compositions

, 2009
У відтворюваних гідродинамічних умовах досліджено характер розчинення CdTe та Cd1-xMnxTe в розчинах системи НІ – Н2О2 – цитратна кислота. Побудовані поверхні однакових швидкостей розчинення (діаграми Гіббса), визначені лімітуючі стадії процесу розчинення
Чернюк О. С., Денисюк Р. О., Томашик З. Ф., Томашик В. М., Гриців В. І.   +4 more
core  

Blow-up behavior of collocation solutions to Hammerstein-type volterra integral equations

, 2013
We analyze the blow-up behavior of one-parameter collocation solutions for Hammerstein-type Volterra integral equations (VIEs) whose solutions may blow up in finite time.
Brunner, Hermann, Yang, Z.W.
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Magnetic and transport properties of cubic Fe1-xZnxO solid solutions with a rock salt structure synthesized at high pressure

Metastable cubic Fe1-xZnxO solid solutions (0 < x ≤ 0.5) with a rock salt structure (Fm-3m) have been synthesized by a solid-phase reaction between wurtzite ZnO and cubic FeO at 7.7 GPa and 1500 K.
Evgeny P., Skipetrov, Andrey N., Baranov, Petr S., Sokolov, Vladimir L., Solozhenko   +3 more
core   +1 more source

A complementary study of perovskites : combining diffraction, solid-state NMR and first principles DFT calculations

, 2011
Perovskites, ABX₃, and their associated solid-solutions are a particularly important and attractive area of research within materials chemistry. Owing to their structural and compositional flexibility and potential physical properties they are one of the
Johnston, Karen Elizabeth
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source