Results 91 to 100 of about 77,032 (268)

Unusual asymmetry in halobenzenes, a solid-state, gas-phase and theoretical investigation

open access: yes, 2011
The molecular structures of 1-Br-4-F-C 6H 4 and 1-Cl-4-F-C 6H 4 have been studied in the gas phase using gas electron diffraction (GED) and ab initio methods. The structure of 1-Cl,4-F-C 6H 4 in the crystalline phase has also been studied, but whilst the
Robertson, H.E.   +5 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The synthesis and polymerisation of some conjugatively extended p-Xylylenes [PDF]

open access: yes, 1991
This thesis describes studies directed towards the preparation of new conjugatively extended p-xylylenes through in situ 1,6- or 1,8-Hoffmann elimination reactions of trimethylammonium salts. The polymers arising from these highly reactive compounds were
Woolley, Martin Fraser
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Defect structure in yttrium, niobium and lead substituted bismuth oxide solid electrolytes

open access: yes, 2009
PhDBismuth oxide based electrolytes are well known for their high oxide ion conductivity at intermediate temperatures (300-700C). Indeed, the defect fluorite structured -phase of Bi2O3 shows the highest known oxide ion conductivity of any material ...
Liu, Xi
core  

The chemistry of some dithiadiazolyls and their platinum complexes [PDF]

open access: yes, 1995
The work outlined in this thesis is mainly concerned with the preparation and reactions of dithiadiazolylium salts, dithiadiazolyls and their Pt complexes.
Dawe, Owen Gerard
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Atomistic simulation of oxide materials with catalytic properties [PDF]

open access: yes, 2009
When supported, thin films demonstrate remarkable structural transformations, with important implications for catalysis, sensors, electrochemistry, semiconductors or superconductors.
Măicăneanu, A.
core  

Crystal chemistry of a new solid solution in the BaO-Bi2O3-Nb2O5 system: Ba-5x/2-Bi(1-x)5/3Nb5O15

open access: yes, 2006
A solid solution of the type Ba5x/2Bi(1-x)5/3Nb5O15 has been identified in the BaO-Bi2O3-Nb2O5 system for the first time. The limits of the solid solution are within the range 0.52
MUKTHA, B.   +10 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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