Results 171 to 180 of about 18,421,260 (248)
Advanced Science, EarlyView.Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang +12 more
wiley +1 more source
Advanced Science, EarlyView.Mesoporous mixed ionic‐electronic PU/PEDOT: PSS electrodes enable label‐free detection of stochastic extracellular bioelectrical dynamics in living Phaeodactylum tricornutum. Living diatoms actively modulate interfacial ionic dynamics, establishing stochastic electrochemical noise as a sensitive probe of microbial bioelectrochemical activity and a new ...
David M. S. Silva +7 more
wiley +1 more source
Advanced Science, EarlyView.The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang +7 more
wiley +1 more source
Advanced Science, EarlyView.Deterministic crypt fission is achieved in intestinal organoids using photopatternable hydrogels with spatiotemporal control. Daughter‐crypt symmetry is shown to depend on parent‐crypt geometry and epithelial curvature, while myosin‐dependent mechanosensing links tissue shape to regenerative outcomes.
Delaney L. McNally +8 more
wiley +1 more source
Advanced Science, EarlyView.An m6A‐modified circRNA, circPSMB1, is identified as a tumor suppressor in chordoma. METTL3‐dependent m6A promotes circPSMB1 interaction with HNRNPA2B1, limiting c‐MYC expression and malignant progression. An injectable HMnO2‐based nanohydrogel enables local circPSMB1 delivery and tumor microenvironment‐responsive therapy, offering a promising strategy
Yingchuang Tang +7 more
wiley +1 more source
Advanced Science, EarlyView.A polymer chain in motion: backbone, ring, and counterion dynamics interlock across timescales to relay protons through poly(ionic liquid) membranes. ABSTRACT Polymer electrolyte membranes composed of ionic liquids (IL), capable of conducting protons efficiently at elevated temperatures, without external humidification, could transform fuel cell ...
Keenan Smith +11 more
wiley +1 more source
Advanced Science, EarlyView.After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin +9 more
wiley +1 more source
Advanced Science, EarlyView.This work is the first to demonstrate the regulation of photoactivated room‐temperature phosphorescence (RTP) and thermally activated delayed fluorescence (TADF) in crystalline materials without any pretreatment. Furthermore, we reveal the underlying mechanisms by uncovering the role of host‐guest energy level alignment, exciton lifetime, crystallinity,
Lisha Zhang +5 more
wiley +1 more source
Advancing Fruit Bioimpedance Monitoring With Sustainable, Soft, And Bio‐Based Electrodes Beyond ECG
Advanced Electronic Materials, EarlyView.Electrical impedance spectroscopy enables non‐destructive fruit quality monitoring, but conventional ECG and needle electrodes compromise signal stability, fruit physiology, and sustainability. This perspective highlights the transition toward soft, biocompatible, and biodegradable electrode interfaces based on natural substrates, bio‐derived ...
Sundus Riaz +6 more
wiley +1 more source
Advanced Electronic Materials, EarlyView.This work presents a sustainable printing and recycling strategy for magnetic sensors designed for IoT applications. By combining solvent‐orthogonal binders with tailored magnetic fillers, the sensors achieve tunable sensitivity across low to high magnetic field ranges.
Rui Xu +6 more
wiley +1 more source