Results 11 to 20 of about 649,583 (215)

Differential Expression of Serum Exosomal miRNAs in Breast CancerPatients and Healthy Controls [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2022
Purpose: Breast cancer has become as a serious public health concern worldwide. Breastcancer cells release exosomes into the circulatory system, which are easily accessible for furtheranalysis like cancer diagnosis. In this study, we aimed to investigate
Rahim Asgari, Jafar Rezaie
doaj   +1 more source

Glioblastoma and the significance of MGMT gene methylation [PDF]

open access: yesReviews in Clinical Medicine, 2014
In this research Glioblastoma has been studied as one of the most common brain tumors and a short review of the available therapeutic methods have presented including surgery, radiotherapy, chemotherapy and particularly adjuvant chemotherapy with ...
Payam Izadpanahi   +2 more
doaj   +3 more sources

Genome-wide mutational signatures in low-coverage whole genome sequencing of cell-free DNA

open access: yesNature Communications, 2022
Detection of mutational signatures in cell-free DNA (cfDNA) is challenging due to low sequence coverage and low mutant allele fractions. Here, the authors identify mutational signatures in plasma whole genome sequencing of cancer patients and use machine
Jonathan C. M. Wan   +7 more
doaj   +1 more source

Evaluation of Pharmacological Effective Concentrations of Aspirin with/without Radiotherapy on MCF-7Breast Cancer Cell Line [PDF]

open access: yesIranian Journal of Veterinary Surgery, 2018
Objective- The studies have been shown that aspirin, an anti-inflammatory agent, could reduce occurrence of different cancers. The aim of the present study was to evaluate pharmacological effective concentrations of aspirin with/without radiotherapy on ...
Negin Farhad   +3 more
doaj   +1 more source

Inhibitory effects of gallic acid on the activity of exosomal secretory pathway in breast cancer cell lines: A possible anticancer impact [PDF]

open access: yesBioImpacts, 2022
Introduction: Breast cancer cells produce exosomes that promote tumorigenesis. The anticancer properties of gallic acid have been reported. However, the mechanism underlying its anticancer effect on the exosomal secretory pathway is still unclear.
Nasrollah Jabbari   +4 more
doaj   +1 more source

Effect of multi-functional polyhydroxylated polyhedral oligomeric silsesquioxane (POSS) nanoparticles on the angiogenesis and exosome biogenesis in human umbilical vein endothelial cells (HUVECs)

open access: yesMaterials & Design, 2021
Angiogenesis, the growth of new vessels, is a vital process for tissue regeneration. Exosomes are nano-sized vesicles releasing from cells that are recognized as important soluble angiogenic factors.
Maryam Feghhi   +6 more
doaj   +1 more source

The Application of PET/CT in Predicting and Evaluating the Therapeutic Response in Chemotherapy of Solid Tumor

open access: yesJournal of Isotopes, 2017
Three aspects of the application of PET/CT in solid tumor chemotherapy were summarized, including the selection of evaluation criteria, the proper time of using PET/CT in the evaluation and the parameters of PET/CT in evaluating the response of ...
positron emission tomography solid tumor chemotherapy predicton of therapeutic response
doaj   +1 more source

Potential therapeutic application of mesenchymal stem cell-derived exosomes in SARS-CoV-2 pneumonia

open access: yesStem Cell Research & Therapy, 2020
Background The outbreak of a new virus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has now become the main health concern all over the world.
Ali Akbari, Jafar Rezaie
doaj   +1 more source

Phase I trial of the TNF-α inhibitor certolizumab plus chemotherapy in stage IV lung adenocarcinomas

open access: yesNature Communications, 2022
Generation of TNF-α in response to chemotherapy has been associated with chemo-resistance and metastasis propagation. Here the authors show that the combination of an anti-TNF antibody and cisplatin doublet chemotherapy increases anti-tumor efficacy in ...
Paul K. Paik   +14 more
doaj   +1 more source

Using CuO nanoparticles and hyperthermia in radiotherapy of MCF-7 cell line: synergistic effect in cancer therapy

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
The aim of this paper was examining the combined impacts of CuO nanoparticles (CuO NPs), hyperthermia (H), and irradiation (R) on an increment of MCF-7 cells.
Hadi Esmaeili Govarchin Ghaleh   +3 more
doaj   +1 more source

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