Results 231 to 240 of about 760,353 (358)

CAR-T cells in solid tumors: engineering, biomarkers, translational pathways and the road ahead. [PDF]

Front Immunol
Al Shaer NSH, Masoud I, Tleyjeh A, Al-Attas AA, Al-Attas MA, Khan MI, Yaqinuddin A.   +6 more
europepmc   +1 more source

Active Learning‐Accelerated Discovery of Fibrous Hydrogels with Tissue‐Mimetic Viscoelasticity

Advanced Functional Materials, EarlyView.
Active learning accelerates the design of fibrous hydrogels that mimic the viscoelasticity of native tissues. By integrating multi‐objective optimization and closed‐loop experimentation, this approach efficiently identifies optimal formulations from thousands of possibilities and decouples elasticity and viscosity. The resulting hydrogels offer tunable
Zhengkun Chen, Zheyuan Miao, Gary Tom, Austin H. Cheng, Elizaveta Gusarova, Benjamen Zondag, Tianyi Wu, Dianoosh Kalhori, Boris Hinz, Milad Abolhasani, Alán Aspuru‐Guzik, Eugenia Kumacheva   +11 more
wiley   +1 more source

Obstacles and improvement strategies for CAR-T cell therapy in solid tumors. [PDF]

Discov Oncol
Luo Z, Hu Q, Ren M, Wang L, Zou Q, Wen X, Chen S, Liu Q, Luo D, Guo Z.   +9 more
europepmc   +1 more source

Self‐Healing and Stretchable Synaptic Transistor

Advanced Functional Materials, EarlyView.
A self‐healing stretchable synaptic transistor (3S‐T) is realized using a p‐PVDF‐HFP‐DBP/PDMS‐MPU‐IU bilayer as gate insulator, where dipole‐dipole interaction enhances polarization to achieve a large memory window. Leveraging its neuronal biomimicry, the synaptic transistor demonstrates electrically compatibility with the biological brain. Furthermore,
Hyongsuk Choo, Sangyong Park, Yoonyi Jeong, Jaepyo Jang, Duhwan Seong, In Soo Kim, Myung‐Gil Kim, Mikyung Shin, Minah Suh, Donghee Son, Jin‐Hong Park   +10 more
wiley   +1 more source

CD24 as an innate immune checkpoint in solid tumors: biology, biomarker stratification, and therapeutic translation. [PDF]

Front Immunol
Zhou W, Huang X, Jia G, Lu C, Ma W.
europepmc   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

T cell immunotherapy for solid tumors: limitations, progress, and future prospects. [PDF]

Front Immunol
Wang Y, Zhang B, Wang Y, Tan Y, Hu X, Che X, Feng M.   +6 more
europepmc   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Clinical applications and future perspectives of circulating tumor cells in solid tumors. [PDF]

Discov Oncol
Hajizadeh A, Momeni F, Eslami NM, Rajeh SM, Parsian A, Birgani RG, Kananpour N, Pourzare P, Aghili A, Samarjan RS, Ghavamikia N, Shayan SK.   +11 more
europepmc   +1 more source

Long‐term effects of crizotinib in ALK‐positive tumors (excluding NSCLC): A phase 1b open‐label study [PDF]

, 2018
et al,, Gambacorti-Passerini, Carlo, Van Tine, Brian A   +2 more
core   +1 more source