Results 21 to 30 of about 2,173,445 (263)
Journal for ImmunoTherapy of Cancer, 2019 Growing evidence suggests a clear role of the host immune system in HER2+ breast cancer. In addition, HER2+ breast cancer is generally considered more immunogenic than hormone receptor-positive (HR+)/HER2-, and specific molecular HER2+ subgroups (e.g ...
Gaia Griguolo +4 more
doaj +1 more source
Role of Bcl-3 in solid tumors [PDF]
, 2011 Bcl-3 is an established oncogene in hematologic malignancies, such as B-cell chronic lymphocytic leukemias. Nevertheless, recent research has shown that it also participates in progression of diverse solid tumors.
Vilma Maldonado +3 more
core +1 more source
Tumor–platelet interaction in solid tumors [PDF]
International Journal of Cancer, 2012 AbstractElevated platelet counts in patients diagnosed with malignant tumors were first described more than 100 years ago. Today it is well known that in many types of solid tumors, thrombocytosis at the time of diagnosis is associated with shorter survival.
Daniel, Buergy +3 more
openaire +2 more sources
Nature Communications, 2023 Drug combinations are key to circumvent resistance mechanisms compromising response to single anti-cancer targeted therapies. The implementation of combinatorial approaches involving MEK1/2 or KRASG12C inhibitors in the context of KRAS-mutated lung ...
Irati Macaya +31 more
doaj +1 more source
Test schemes covered under MPQAP EQAS program for solid tumors.
, 2022 Test schemes covered under MPQAP EQAS program for solid tumors.
Ramya Iyer (13844211) +9 more
core +1 more source
Clinical, pathological, and PAM50 gene expression features of HER2-low breast cancer
npj Breast Cancer, 2021 Novel antibody-drug conjugates against HER2 are showing high activity in HER2-negative breast cancer (BC) with low HER2 expression (i.e., 1+ or 2+ and lack of ERBB2 amplification). However, the clinical and molecular features of HER2-low BC are yet to be
Francesco Schettini +26 more
doaj +1 more source
FGF21 and APOA1 mRNA-based therapies for the treatment of experimental acute pancreatitis
Journal of Translational MedicineBackground Acute pancreatitis (AP) presents a significant clinical challenge with limited therapeutic options. The complex etiology and pathophysiology of AP emphasize the need for innovative treatments.
Amaya Lopez-Pascual +18 more
doaj +1 more source
Molecular Oncology, 2020 Development of precision medicine for malignant pleural mesothelioma (MPM) requires a deep knowledge of tumor heterogeneity. Histologic and molecular classifications and histo‐molecular gradients have been proposed to describe heterogeneity, but a deeper
Lisa Quetel +20 more
doaj +1 more source
, 2007 Uniform DNA distribution in tumors is a prerequisite step for high transfection efficiency in solid tumors. To improve the transfection efficiency of electrically assisted gene delivery to solid tumors in vivo, we explored how tumor histological ...
Grosel, A. +7 more
core +1 more source
Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
Pediatric Blood &Cancer, EarlyView.ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan +18 more
wiley +1 more source