Results 91 to 100 of about 113,242 (268)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Phase-field approach to polycrystalline solidification including heterogeneous and homogeneous nucleation [PDF]
, 2008 Advanced phase-field techniques have been applied to address various aspects of polycrystalline solidification including different modes of crystal nucleation.
Granasy, L +6 more
core +2 more sources
Cailiao gongchengOxide eutectic ceramics have excellent high specific strength, high temperature resistance, corrosion resistance, oxidation and creep resistance, and so on, which are considered to be the promising materials to be used in ultra-high temperature oxidation,
YAO Jiatong +7 more
doaj +1 more source
A Solidification Model for Atomization
ISIJ International, 2009 A microsegregation solidification model has been extended for an individual droplet falling through a stagnant gas during the atomization process. Assuming a uniform temperature within the droplet, the model takes into account nucleation undercooling and equiaxed growth of the dendritic and eutectic microstruc-tures until complete solidification.1 It ...
Prasad, Arvind +3 more
openaire +5 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Materials Research LettersIn this work, different transformed β matrix was obtained in Ti–5Al–7.5 V alloy. The alloy with equiaxed αp phase and transformed β matrix containing α′ martensite and β phase exhibits good combination of strength and plasticity, as well as a high work ...
Sisi Xie +8 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Directional solidification of type AA3003 alloys with addition of Zn and Si
, 2004 Directional solidification has been used to study effects on the structure and on materials properties from variations in the alloy contents in type AA 3003 alloys, Structure parameters such as grain size, DAS and secondary phase precipitations have been
Jaradeh, Majed, Carlberg, Torbjörn
core +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source