Results 111 to 120 of about 385,356 (336)

Investigations of fluid flow effects on dendritic solidification: Consequences on fragmentation, macrosegregation and the influence of electromagnetic stirring [PDF]

, 2017
N. Shevchenko, H. Neumann-Heyme, C. Pickmann, E Schaberger-Zimmermann, G. Zimmermann, K. Eckert, S. Eckert, N. Shevchenko, H. Neumann-Heyme, C. Pickmann, E Schaberger-Zimmermann, G. Zimmermann, K. Eckert, S. Eckert   +13 more
openalex   +1 more source

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

Solidification in a Supercomputer: From Crystal Nuclei to Dendrite Assemblages

JOM, 2015
Thanks to the recent progress in high-performance computational environments, the range of applications of computational metallurgy is expanding rapidly.
Y. Shibuta, M. Ohno, T. Takaki
semanticscholar   +1 more source

Analysis and calculation of macrosegregation in a casting ingot. MPS solidification model. Volume 1: Formulation and analysis [PDF]

The physical and numerical formulation of a model for the horizontal solidification of a binary alloy is described. It can be applied in an ingot. The major purpose of the model is to calculate macrosegregation in a casting ingot which results from flow ...
Maples, A. L., Poirier, D. R.
core   +1 more source

Multiphase imaging of freezing particle suspensions by confocal microscopy

, 2017
Ice-templating is a well-established processing route for porous ceramics. Because of the structure/properties relationships, it is essential to better understand and control the solidification microstructures.
Dedovets, Dmytro, Deville, Sylvain
core   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Optimization of directional energy deposition forming process of high-strength aluminum alloy based on laser mode control

Cailiao gongcheng
Due to the low boiling points of the main constituents of 7075 aluminum alloy and the high surface tension gradient of the molten alloy， combined with the uneven energy distribution of the circular Gaussian （CG） laser beam spot commonly used in directed ...
SHI Donglai, JIA Chewang, SUN Liushuo, ZHAO Yufan, YANG Haiou, LIN Xin   +5 more
doaj   +1 more source

Quantum thermodynamics at critical points during melting and solidification processes

, 2014
We systematically explore and show the existence of finite-temperature continuous quantum phase transition (CTQPT) at a critical point, namely, during solidification or melting such that the first-order thermal phase transition is a special case within ...
A. D. Arulsamy, AD Arulsamy, AD Arulsamy, AD Arulsamy, AD Arulsamy, AD Arulsamy, AD Arulsamy, AD Arulsamy, C Ramakrishnan, CS Snow, CV Raman, CV Raman, CV Raman, CV Raman, F Isik, GN Ramachandran, GN Ramachandran, L Cemič, M Lavagna, M Vojta, R Shankar, R Shankar, R Shankar, S Sachdev, SC Gairola, SV Lishchuk, T Vojta, V Tchijov   +27 more
core   +1 more source