Results 91 to 100 of about 17,105 (305)

Energy-Harvesting Performance of Twin-Rotor Vertical-Axis Wind Turbines with Phase Interference Under Different Solidities

Journal of Marine Science and Engineering
This paper aims to investigate the aerodynamic variation patterns of twin-rotor vertical-axis wind turbines (TR-VAWTs) considering phase interference under different solidities, and to reveal the interactive mechanism between solidity, phase interference,
Miankui Wu, Renwei Ji, Peng Dou, Chenghang Gao, Yuquan Zhang, Jianhua Zhang, Linfeng Chen, Emmanuel Fernandez-Rodriguez   +7 more
doaj   +1 more source

A Massive Analysis of Ethereum Smart Contracts Empirical Study and Code Metrics

IEEE Access, 2019
In this work, we perform a comprehensive empirical study of smart contracts deployed on the ethereum blockchain. The objective of the analysis is to provide empirical results on smart contracts features, smart contract transactions within the blockchain,
Andrea Pinna, Simona Ibba, Gavina Baralla, Roberto Tonelli, Michele Marchesi   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Experimental and numerical investigations of actuator disks for wind turbines

Energy Science & Engineering, 2020
The expenses of a wind turbine modeling in particular a wind farm modeling either numerically or experimentally cause to take the advantages of actuator disks (AD).
Mohammad Hassan Ranjbar, Hadi Zanganeh Kia, Seyyed Abolfazl Nasrazadani, Kobra Gharali, Jatin Nathwani   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Defects and Vulnerabilities in Smart Contracts, a Classification using the NIST Bugs Framework

International Journal of Networked and Distributed Computing (IJNDC)
Rising to popularity in the last decade, blockchain technology has become the preferred platform for the transfer of digital currency. Unfortunately, many of these environments are rife with vulnerabilities exploited by financially motivated attackers ...
Wesley Dingman, Aviel Cohen, Nick Ferrara, Adam Lynch, Patrick Jasinski, Paul E. Black, Lin Deng   +6 more
doaj   +1 more source

The Stability at the Solid-Solid and Liquid-Solid Interfaces

, 2016
In this thesis, we studied three small subjects in the realm of continuum mechanics: imbibition in fluid mechanics, beam and rod buckling in solid mechanics and shell buckling at the solid-liquid interface. In chapter 2, we examined the radial imbibition into a homogenous semi-infinite porous media from a point source with infinite liquid supply.
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

A Study of Ethereum’s Transition from Proof-of-Work to Proof-of-Stake in Preventing Smart Contracts Criminal Activities

Network
With the ever-increasing advancement in blockchain technology, security is a significant concern when substantial investments are involved. This paper explores known smart contract exploits used in previous and current years. The purpose of this research
Oliver J. Hall, Stavros Shiaeles, Fudong Li   +2 more
doaj   +1 more source