Results 101 to 110 of about 993,461 (297)

Super-geometric electron focusing on the hexagonal Fermi surface of PdCoO2

Nature Communications, 2019
Ballistic electron beams in clean metals can be focused by passing currents through well designed contraptions, which is mostly done in isotropic materials described by a circular Fermi surface.
Maja D. Bachmann, Aaron L. Sharpe, Arthur W. Barnard, Carsten Putzke, Markus König, Seunghyun Khim, David Goldhaber-Gordon, Andrew P. Mackenzie, Philip J. W. Moll   +8 more
doaj   +1 more source

Do Athermal Amorphous Solids Exist?

, 2011
We study the elastic theory of amorphous solids made of particles with finite range interactions in the thermodynamic limit. For the elastic theory to exist one requires all the elastic coefficients, linear and nonlinear, to attain a finite thermodynamic
D. Jang, Edan Lerner, H. G. E. Hentschel, Itamar Procaccia, Smarajit Karmakar, W. Weibull   +5 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Coulomb interactions in high-coherence femtosecond electron pulses from tip emitters

Structural Dynamics, 2019
Tip-based photoemission electron sources offer unique properties for ultrafast imaging, diffraction, and spectroscopy experiments with highly coherent few-electron pulses.
Nora Bach, Till Domröse, Armin Feist, Thomas Rittmann, Stefanie Strauch, Claus Ropers, Sascha Schäfer   +6 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Concurrence of directional Kondo transport and incommensurate magnetic order in the layered material AgCrSe2

Communications Physics
In this work, we report on the concurrent emergence of the directional Kondo behavior and incommensurate magnetic ordering in a layered material. We employ temperature- and magnetic field-dependent resistivity measurements, susceptibility measurements ...
José Guimarães, Dorsa S. Fartab, Michal Moravec, Marcus Schmidt, Michael Baenitz, Burkhard Schmidt, Haijing Zhang   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Orbital selective commensurate modulations of the local density of states in ScV6Sn6 probed by nuclear spins

Nature Communications
The kagome network is a unique platform that harbors a diversity of special electronic states due to its inherent band structure features comprising Dirac cones, van Hove singularities, and flat bands. Some kagome-based metals have recently been found to
Robin Guehne, Jonathan Noky, Changjiang Yi, Chandra Shekhar, Maia G. Vergniory, Michael Baenitz, Claudia Felser   +6 more
doaj   +1 more source

Resonant torsion magnetometry in anisotropic quantum materials

Nature Communications, 2018
Insights into the behavior of quantum materials are only possible because of the development of suitable experimental probes. Modic et. al. develop the theoretical and experimental basis for resonant torsion magnetometry—a technique to measure ...
K. A. Modic, Maja D. Bachmann, B. J. Ramshaw, F. Arnold, K. R. Shirer, Amelia Estry, J. B. Betts, Nirmal J. Ghimire, E. D. Bauer, Marcus Schmidt, Michael Baenitz, E. Svanidze, Ross D. McDonald, Arkady Shekhter, Philip J. W. Moll   +14 more
doaj   +1 more source