Results 81 to 90 of about 993,461 (297)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Embedded discontinuities for softening solids [PDF]
, 1999 Additional, discontinuous functions are added to the displacement field of standard finite elements in order to capture highly localised zones of intense straining.
Sluys, LJ, Wells, GN
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The Evolution of Protoplanetary Disks Around Millisecond Pulsars: The PSR 1257 +12 System
, 2007 We model the evolution of protoplanetary disks surrounding millisecond pulsars, using PSR 1257+12 as a test case. Initial conditions were chosen to correspond to initial angular momenta expected for supernova-fallback disks and disks formed from the ...
Brad Hansen +10 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Crude glycerin in anaerobic co-digestion of dairy cattle manure increases methane production
Scientia AgricolaAnaerobic digestion of crude glycerin (CG) along with animal waste has been an excellent option for increasing the production of biogas and methane to achieve efficiency in the treatment of both residues.
Silvana Simm +5 more
doaj +1 more source
, 2009 This is a written version of a popular science talk for school children given on India's National Science Day 2009 at Mumbai. I discuss what distinguishes solids, liquids and gases from each other.
Dhar, Deepak
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
AgronomyCapsicum spp. support diverse fresh and processing value chains, yet integrated assessments of phenotypic stability and genome-enabled prediction remain limited.
Sebastian Parra-Londono +5 more
doaj +1 more source
Multiple Dirac cones at the surface of the topological metal LaBi
Nature Communications, 2017 The magnetoresistance suggests an exotic topological phase in LaBi, but the evidence is still missing. Here, Nayaket al. report the existence of surface states of LaBi through the observation of three Dirac cones, confirming it a topological semimetal.
Jayita Nayak +10 more
doaj +1 more source