Results 71 to 80 of about 993,461 (297)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Sampling eigenmodes in colloidal solids
We study the properties of correlation matrices widely used in the characterisation of vibrational modes in colloidal materials. We show that the eigenvectors in the middle of the spectrum are strongly mixed, but that at both the top and the bottom of ...
Maggs, A. C., Schindler, M.
core +3 more sources
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Flow properties of suspensions rich in solids [PDF]
Mathematical evaluation of flow properties of fluids carrying high concentrations of solids in suspension relates suspension viscosity to physical properties of the solids and liquids, and provides a means for predicting flow behavior.
Armstrong, W. P. +2 more
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We describe the fractal solid by a special continuous medium model. We propose to describe the fractal solid by a fractional continuous model, where all characteristics and fields are defined everywhere in the volume but they follow some generalized ...
Christensen R. M. +7 more
core +2 more sources
10 pages.
Bordin, Lorenzo +3 more
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
It is suggested that at the melting temperature the thermal phonon vibration is in self-resonance with the lattice vibration of the surface atomic/molecular layer.
Apai +57 more
core +1 more source

