Results 121 to 130 of about 4,042,902 (260)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
PENDEKATAN TECHNOLOGY ACCEPTANCE MODEL UNTUK MENGUJI PERSEPSI RESIKO ADOPSI E-BANKING
Benefit Jurnal Manajemen dan Bisnis, 2013 The purpose of this paper is to identify risk factors that discourage consumers from adopting e-banking services. Perceived risk is a key construct in consumer decision making, whereas whether this is true in e-banking market is rarely researched.
Edy Purwo Saputro, Fereshti Nurdiana
doaj
, 1999 Passion Symphony for organ solo in five movements. Large-scale work lasting 2 hrs and 05 mins., intended for recital use linked to the liturgy of the Church ...
Pott, Francis
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Composers' Forum Concert, October 14, 1993 [PDF]
, 1993 This is the concert program of the Composers' Forum Concert on Thursday, October 14, 1993 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue.
School of Music, Boston University
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
ANTESEDEN RISK DAN TRUST YANG MEMPENGARUHI SIKAP INDIVIDU TERHADAP NIAT ADOPSI E-BANKING
Benefit Jurnal Manajemen dan Bisnis, 2012 The e-banking adoption researches have been conducted with diversity in the approach models in which they found the model diversity so that these are casuistic. This fact becomes an interesting gap research.
Edy Purwo Saputro +1 more
doaj
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source