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False positive urine amphetamine immunoassay due to solriamfetol
Sleep Medicine, 2023Solriamfetol is a schedule IV-controlled substance used to treat excessive daytime sleepiness resulting from narcolepsy or obstructive sleep apnea. We present a patient prescribed solriamfetol who tested positive for amphetamines on a routine urinary toxicology screen despite patient denial of illicit drug use, raising the possibility of a false ...
Gopal, Kumar +5 more
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Behandlung einer symptomatischen Hypersomnie mit Solriamfetol
Nervenheilkunde, 2021ZUSAMMENFASSUNGEs wird der Fall eines 34 Jahre alten Patienten berichtet, der nach einer Epstein-Barr-Virus-Infektion eine symptomatische Hypersomnie entwickelt hat. Diese Hypersomnie konnte mit konventionellen Substanzen nicht befriedigend gebessert werden. Unter Solriamfetol kam es zu einer signifikanten Besserung der exzessiven Tagesschläfrigkeit.
Susan Wald, Stefan Evers
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Solriamfetol: First Global Approval
Drugs, 2019Solriamfetol (Sunosi™) is an orally active, selective dopamine and norepinephrine reuptake inhibitor that was recently approved in the USA as a treatment for excessive daytime sleepiness (hypersomnia) associated with narcolepsy and obstructive sleep apnoea (OSA).
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Preclinical Pharmacology of Solriamfetol: Potential Mechanisms for Wake Promotion
CNS Spectrums, 2023AbstractIntroductionSolriamfetol is a wake-promoting agent (WPA) approved for the treatment of excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea. The wake-promoting mechanism of solriamfetol may result from dopamine and norepinephrine reuptake inhibition.
Hema Gursahani +7 more
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Solriamfetol for Excessive Sleepiness in Narcolepsy and Obstructive Sleep Apnea
Annals of Pharmacotherapy, 2020Objective: The purpose of this article is to review the available clinical trial data that led to the Food and Drug Administration (FDA) approval of solriamfetol as well as its role in clinical practice. Data Sources: A MEDLINE/PubMed search was conducted (January 2000 to February 2020) using the keyword solriamfetol to discover appropriate clinical ...
Jason Powell +2 more
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Solriamfetol for Attention-Deficit/Hyperactivity Disorder in Adults
The Journal of Clinical Psychiatry, 2023Objective: Some individuals with attention-deficit/hyperactivity disorder (ADHD) may not tolerate or adequately respond to currently available treatments. This study examined whether solriamfetol could have a favorable pattern of effects and tolerability as a treatment for ADHD in adults.Methods: Sixty adults with DSM-5 ADHD participated from August ...
Craig B H, Surman +5 more
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Journal of Analytical Toxicology, 2023
Abstract Urine drug screening by immunoassay is a common method to quickly identify drug exposures in the emergency setting and to detect unexpected drug exposures in a variety of patient care and occupational health settings. Although they provide rapid results, immunoassays are susceptible to cross-reactivity with other medications and
Ashley R Rackow, Claire E Knezevic
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Abstract Urine drug screening by immunoassay is a common method to quickly identify drug exposures in the emergency setting and to detect unexpected drug exposures in a variety of patient care and occupational health settings. Although they provide rapid results, immunoassays are susceptible to cross-reactivity with other medications and
Ashley R Rackow, Claire E Knezevic
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Solriamfetol for the treatment of daytime sleepiness in obstructive sleep apnea
Expert Review of Respiratory Medicine, 2018Introduction: Obstructive sleep apnea (OSA) is highly prevalent and constitutes a major health hazard. Current pharmacotherapy is ineffective in correcting sleep-disordered breathing and is used adjunctively to address residual sleepiness. A new drug, solriamfetol, a selective norepinephrine-dopamine reuptake inhibitor, is the first drug of its class ...
Vivien C. Abad, Christian Guilleminault
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Solriamfetol for the treatment of excessive daytime sleepiness associated with narcolepsy
Expert Review of Clinical Pharmacology, 2019Introduction: Narcolepsy is a chronic disabling condition, excessive daytime somnolence is the main symptoms of it. There is currently no cure for narcolepsy, and hence there is a great need for new treatment options. Solriamfetol is a new selective dopamine and norepinephrine reuptake inhibitor with robust wake-promoting effects.
Junyi, Yang, Junfa, Gao
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Solriamfetol in excessive daytime sleepiness: a profile of its use
Drugs & Therapy Perspectives, 2020Oral solriamfetol (Sunosi™), a selective dopamine and norepinephrine reuptake inhibitor, is approved to improve wakefulness in adults with excessive daytime sleepiness (EDS) associated with narcolepsy or obstructive sleep apnoea (OSA) in the USA and EU.
Emma D. Deeks, Young-A Heo
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