Results 111 to 120 of about 609,910 (308)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Differential solubility test for haemoglobin S [PDF]

open access: yes, 1980
This article presents results of two hundred and seventy-eight blood specimens which were examined, both by the Sickle-quik solubility test and haemoglobin electrophoresis on paper.Two hundred and seventy-eight blood specimens were examined ...
Bhushan, V., Masona, J., Chintu, C.
core   +2 more sources

Cyclodextrin-Based Nanotransporters as a Versatile Tool to Manage Oxidative Stress-Induced Lung Diseases

open access: yesAntioxidants
Oxidative stress is one of the key elements in lung-related complications such as cystic fibrosis, acute lung injury, pulmonary hypertension, bronchopulmonary dysplasia, chronic airway diseases, lung cancer, COVID-19, and many others.
Supandeep Singh Hallan   +3 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

The Development of Transdermal Piroxicam Using HPMC Matrices With PVP K-30 as a Penetration Enhancer [PDF]

open access: yes, 2006
The physicochemical properties such as solubility, partition coefficient, and membrane permeability of a drug are required for formulating and estimating drugs absorption that pass through biological membranes.
Aryani, Ni Luh Dewi
core   +1 more source

Carbon Dioxide Absorption by Polyethylene Glycol Dimethyl Ether Modified by 2-methylimidazole

open access: yesSeparations
Developing and utilizing capture and storage technologies for CO2 has become a critical research topic due to the significant greenhouse effect caused by excessive CO2 emissions.
Yan Wu   +10 more
doaj   +1 more source

Solubility-driven successful drug discovery

open access: yes, 2008
Solubility is an important physico-chemical parameter in drug discovery as well as development since it affects both in vitro and in vivo assay results. With the trend towards lipophilic compounds, finding an optimal strategy to assess solubility earlier
Yang, Linhong   +3 more
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Comment on "Thermochemical Investigations of Associated Solutions: Calculation of Solute-Solvent Equilibrium Constants from Solubility Measurements"

open access: yes, 1987
This article provides comments on "Thermochemical Investigations of Associated Solutions: Calculation of Solute-Solvent Equilibrium Constants from Solubility Measurements," published in the Journal of Pharmaceutical Sciences in ...
Acree, William E. (William Eugene)
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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