Results 121 to 130 of about 527,537 (317)
AntioxidantsOxidative stress is one of the key elements in lung-related complications such as cystic fibrosis, acute lung injury, pulmonary hypertension, bronchopulmonary dysplasia, chronic airway diseases, lung cancer, COVID-19, and many others.
Supandeep Singh Hallan +3 more
doaj +1 more source
Solubility of acetaminophen in polyethylene glycol 400 + water mixtures according to the extended hildebrand solubility approach [PDF]
, 2012 The Extended Hildebrand Solubility Approach(EHSA) was applied in the presentwork to evaluate the solubility of theanalgesic drug acetaminophen (paracetamol)in polyethylene glycol 400 + watermixtures at 298.15 K.
Ahumada, Edgar +2 more
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Carbon Dioxide Absorption by Polyethylene Glycol Dimethyl Ether Modified by 2-methylimidazole
SeparationsDeveloping and utilizing capture and storage technologies for CO2 has become a critical research topic due to the significant greenhouse effect caused by excessive CO2 emissions.
Yan Wu +10 more
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Solubility-driven successful drug discovery
, 2008 Solubility is an important physico-chemical parameter in drug discovery as well as development since it affects both in vitro and in vivo assay results. With the trend towards lipophilic compounds, finding an optimal strategy to assess solubility earlier
Yang, Linhong +3 more
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Glycerol for improving solubility and evaluation of antimicrobial activity for natural products [PDF]
, 2016 With this study, we aimed to improve solubility and provide enhanced evaluation of antimicrobial activity with the addition of glycerol as a co-solvent with DMSO.
NC DOCKS at The University of North Carolina at Greensboro +1 more
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