Results 41 to 50 of about 1,433,465 (359)
Incompatibility of antimalarial drugs: challenges in formulating combination products for malaria
Drug DeliveryLipophilic drugs require more advance formulation, especially if the intention is to make solutions or semisolid formulations. This also accounts for most antimalarial drugs. Although some of these antimalarial drugs are soluble in lipid vehicles, few of
Ellen K. G. Mhango +3 more
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Molecules, 2017 Emodin is a component in a Chinese herb, Rheum officinale Baill, traditionally used for diabetes and anticancer. Its poor solubility is one of the major challenges to pharmaceutical scientists.
Eunmi Ban +6 more
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Impact of Dendrimers on Solubility of Hydrophobic Drug Molecules
Frontiers in Pharmacology, 2017 Adequate aqueous solubility has been one of the desired properties while selecting drug molecules and other bio-actives for product development. Often solubility of a drug determines its pharmaceutical and therapeutic performance.
Sonam Choudhary +4 more
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Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
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Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
International Journal of Food Properties, 2020 In this research, complex coacervation between oak protein isolate (OPI) and gum arabic (GA) at different pH values (7.0–1.6) and mixing ratios (8:1 to 1:8 protein: polysaccharide), and a constant biopolymer concentration (0.125% w/w) was studied by ...
Behnaz Naderi +3 more
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The Theory of Solubility [PDF]
The Journal of Physical Chemistry, 1912 n ...
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Nature, 1952 IN further attempts to find a solvent for melanin which would be of use in histological work, the following substances have been found to dissolve, in the cold, the pigments extracted from the ink sac of Sepia officinalis and melanoma tissue, and those prepared from adrenaline and 3,4-dihydroxyphenylalanine (dopa): ethylene glycol monomethyl ether ...
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Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
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Formation of Metastable Solid Solutions in Bi-Ge Films during Low-Temperature Treatment
MetalsWe investigated the mechanism and kinetics of the formation of metastable BiGe solid phases during the amorphous-to-crystalline transformation of Ge films in contact with Bi.
Sergiy Bogatyrenko +3 more
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