Results 41 to 50 of about 2,048,035 (343)

Advances in Nanotechnology for Enhancing the Solubility and Bioavailability of Poorly Soluble Drugs

Drug Design, Development and Therapy
This manuscript offers a comprehensive overview of nanotechnology’s impact on the solubility and bioavailability of poorly soluble drugs, with a focus on BCS Class II and IV drugs.
Yifan Liu, Yushan Liang, Yuhong Jing, Peng Xin, J. Han, Yongle Du, Xinru Yu, Runhe Zhu, Mingxun Zhang, Wen Chen, Yingjie Ma   +10 more
semanticscholar   +1 more source

Calculation of solubility in titanium alloys from first-principles

, 2009
We present an approach to calculate the atomic bulk solubility in binary alloys based on the statistical-thermodynamic theory of dilute lattice gas. The model considers all the appropriate ground states of the alloy and results in a simple Arrhenius-type
Akbarzadeh, Bligaard, Blochl, Calandra, Cava, Ceder, Ceder, Chen, Chepulskii, Clouet, Curtarolo, Curtarolo, Curtarolo, de Fontaine, Fischer, Friedel, Hart, Harutyunyan, Johannesson, Kolmogorov, Kolmogorov, Kolmogorov, Korzhavyi, Kresse, Krivoglaz, Matysina, Mishin, Mishin, Morgan, Perdew, Persson, Roman V. Chepulskii, Siegel, Singh, Stefano Curtarolo, Stucke, van de Walle, Van der Ven, Villars, Wagner, Wolverton, Xu   +41 more
core   +1 more source

The solubility and oxidation state of nickel in silicate melt at low oxygen fugacities: Results using a mechanically assisted equilibration technique [PDF]

, 1994
The solubility of Ni in a silicate melt has been measured using a new, mechanically assisted equilibration technique over a wide range of controlled ƒO2 values.
Dingwell, Donald B., Ertel, Werner, O'Neill, Hugh St. C., Spettel, Bernhard   +3 more
core   +1 more source

Versatile Solid Modifications of Multicomponent Pharmaceutical Salts: Novel Metformin–Rhein Salts Based on Advantage Complementary Strategy Design

Pharmaceutics, 2023
This study aimed to develop an effective treatment for diabetes and diabetic complications, based on the advantage complementary strategy of drug–drug salt, by designing and synthesizing the multicomponent molecular salts containing metformin (MET) and ...
Mingchao Yu, Meidai Liang, Qi An, Wenwen Wang, Baoxi Zhang, Shiying Yang, Jian Zhou, Xiuying Yang, Dezhi Yang, Li Zhang, Guanhua Du, Yang Lu   +11 more
doaj   +1 more source

Temperature impact assessment on struvite solubility product: a thermodynamic modeling approach [PDF]

, 2011
This work addresses the problem of phosphorus recovery from wastewater by struvite precipitation, which is chemically known as magnesium ammonium phosphate hexahydrate MgNH4PO4·6H2O.
Azzaro-Pantel, Catherine, Biscans, Béatrice, Freche, Michèle, Hanhoun, Mary, Montastruc, Ludovic, Pibouleau, Luc   +5 more
core   +3 more sources

Effect of Solvent Composition on Solubility, Thermodynamics, Metastable Zone Width (MSZW) and Crystal Habit of L-Ascorbic Acid

Crystals, 2022
This work investigates the effect of different solvent systems on solubility, thermodynamics, metastable zone width (MSZW), and crystal habit of ascorbic acid, in order to help optimize its crystallization process.
Jyoti Yadav, Dan G. Dumitrescu, Thomas Kendall, Carmen Guguta, Swati A. Patel   +4 more
doaj   +1 more source

Automation potential of a new, rapid, microscopy based method for screening drug-polymer solubility [PDF]

, 2020
For the pharmaceutical industry, the preformulation screening of the compatibility of drug and polymeric excipients can often be time-consuming because of the use of trial-and-error approaches.
Alhijjaj, Muqdad, Belton, Peter, Fabian, Laszlo, Qi, Sheng, Reading, Mike   +4 more
core   +1 more source

A Novel Cocrystal of Daidzein with Piperazine to Optimize the Solubility, Permeability and Bioavailability of Daidzein

Molecules
It is well known that daidzein has various significant medicinal values and health benefits, such as anti-oxidant, anti-inflammatory, anti-cancer, anti-diabetic, cholesterol lowering, neuroprotective, cardioprotective and so on.
Zhipeng Wang, Shuang Li, Qi Li, Wenwen Wang, Meiru Liu, Shiying Yang, Li Zhang, Dezhi Yang, Guanhua Du, Yang Lu   +9 more
doaj   +1 more source

Synthesis of Purine-Based Ionic Liquids and Their Applications

Molecules, 2021
Bio-based ionic liquids (ILs) are being increasingly sought after, as they are more sustainable and eco-friendly. Purines are the most widely distributed, naturally occurring N-heterocycles, but their low water-solubility limits their application.
Ana R. F. Carreira, Telma Veloso, Nicolas Schaeffer, Joana L. Pereira, Sónia P. M. Ventura, Cécile Rizzi, Juliette Sirieix Plénet, Helena Passos, João A. P. Coutinho   +8 more
doaj   +1 more source

Exploring Preferences for a Digital Single‐Session Intervention for Adolescent Siblings of Youth With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro, Sarah Silver, Prishi Patel, Meredith K. Reffner Collins, Kimberly S. Canter, Stephanie Fooks‐Parker, Michael Amylon, Shawna V. Hudson, Jessica L. Schleider, Melissa A. Alderfer, Katie A. Devine   +10 more
wiley   +1 more source