Results 51 to 60 of about 1,983,588 (386)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Comparative evaluation of physical and chemical properties of calcium silicate-based root-end filling materials (Mineral trioxide aggregate and biodentine): An in vitro study

Indian Journal of Dental Sciences, 2018
Aims: Evaluation and comparison of solubility, pH, and calcium ion release of calcium-silicate based root-end filling materials mineral trioxide aggregate (MTA) and biodentine. Methodology: The total sample size for the study was 120.
Shilpa Kumari, Anika Mittal, Shifali Dadu, Aditi Dhaundiyal, Anju Abraham, Bidya Yendrembam   +5 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

In Vitro Screening of the Apatite-Forming Ability, Biointeractivity and Physical Properties of a Tricalcium Silicate Material for Endodontics and Restorative Dentistry

Dentistry Journal, 2013
Aim: Calcium silicate-based materials are hydraulic self-setting materials with physico-chemical properties suitable for endodontic surgery and good biological/clinical outcomes.
Maria Giovanna Gandolfi, Francesco Siboni, Antonella Polimeni, Maurizio Bossù, Francesco Riccitiello, Sandro Rengo, Carlo Prati   +6 more
doaj   +1 more source

Solubility of Systems of Quadratic Forms [PDF]

, 1997
We derive an upper bound for the least number of variables needed to guarantee that a system of t quadratic forms (t>=2) over a field F has a nontrivial zero.
Martin, Greg
core   +2 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Drug‑Drug and Drug‑Nutraceutical Cocrystal/Salt as Alternative Medicine for Combination Therapy: A Crystal Engineering Approach

Crystals, 2018
The pre-formulation of pharmaceutical cocrystals and salts is a concept of crystal engineering that has emerged as a promising technique for drug development in pharmaceutical industry.
Ranjit Thakuria, Bipul Sarma
doaj   +1 more source

The Role of Microenvironment Reagent Solubility on Reaction Kinetics of 4-Nitrophenol Reduction [PDF]

, 2018
The Role of Microenvironment Reagent Solubility on Reaction Kinetics of 4-Nitrophenol Reduction Michael Zeevi1 with Andrew Harrison1 and Christina Tang, PhD1 1Department of Chemical and Life Science Engineering, VCU School of Engineering Introduction ...
Harrison, Andrew, Tang, Christina, Zeevi, Michael P   +2 more
core   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Solubility Improvement of Benexate through Salt Formation Using Artificial Sweetener

Pharmaceutics, 2018
Benexate, a drug used clinically as a defensive type anti-ulcer agent, has poor solubility and a bitter taste. To improve its solubility, a crystal engineering approach was proposed with the formation of novel salts using an artificial sweetener as a ...
Okky Dwichandra Putra, Daiki Umeda, Eriko Fujita, Tamami Haraguchi, Takahiro Uchida, Etsuo Yonemochi, Hidehiro Uekusa   +6 more
doaj   +1 more source