Results 51 to 60 of about 514,430 (322)
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Development and Structural Behaviour of Soybean Gelato
The aim of this study is to elaborate and evaluate structural characteristics of soybean gelato by varying the content of soybean protein concentrate (2.95 to 17.05 %) and vegetable fat (7.95 to 22.05 %) using experimental design. The replacement of milk
Juliana Savio+10 more
doaj +1 more source
Water uptake and solubility of Acroseal sealer in comparison with Apexit and AH Plus sealers in Hank’s solution [PDF]
Introduction. The function of root canal fillings is to seal the root canal system. The important physical property necessary for sealers to achieve this is low solubility.
Grga Đurica+3 more
doaj +1 more source
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Solubility of organic salts in solvent-antisolvent mixtures: A combined experimental and molecular dynamics simulations approach [PDF]
We combine molecular dynamics simulations with experiments to estimate solubilities of organic salts in complex growth environments. We predict the solubility by simulations of the growth and dissolution of ions at the crystal surface kink sites at different solution concentrations.
arxiv
Xiangrong Zhang,1,2,* Yi Zhang,1,* Shuang Guo,3 Feifei Bai,1 Tong Wu,1 Yuqing Zhao1 1Department of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education, 2Department of Pharmaceutics ...
Zhang X+5 more
doaj
Sweet potato starch characteristic of local variety using heat moisture treatment with different level of moisture content and temperature The aim of this study is to modify local variety sweet potato starch (cream flesh color) in order to produce the ...
Virna Muhardina+4 more
doaj +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Introduction: Soft denture liners have a key role in modern removable prosthodontics since they restore health to inflamed and abused mucosa by redistribution of forces transmitted to the edentulous ridges. The most common problems encountered using soft
Aditi Garg, K Kamalakanth Shenoy
doaj
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source