Results 151 to 160 of about 2,906,554 (204)

Tactics to Improve Solubility

2021
To reach the site of therapeutic action a drug molecule must possess adequate aqueous solubility to deliver an efficacious dose. This chapter gives an overview of aqueous solubility measures and models pertinent to drug discovery, whilst putting these solubility levels into context. Solubility is inexorably linked to other physicochemical properties of
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Salt formation to improve drug solubility

Advanced Drug Delivery Reviews, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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Oral formulation strategies to improve solubility of poorly water-soluble drugs

Expert Opinion on Drug Delivery, 2011
In the past two decades, there has been a spiraling increase in the complexity and specificity of drug-receptor targets. It is possible to design drugs for these diverse targets with advances in combinatorial chemistry and high throughput screening. Unfortunately, but not entirely unexpectedly, these advances have been accompanied by an increase in the
Abhishek, Singh, Zelalem Ayenew, Worku, Guy, Van den Mooter   +2 more
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Improving solubility of fisetin by cocrystallization

CrystEngComm, 2014
Fisetin, a naturally occurring polyphenolic compound, has a proven record of in vitro demonstrated anti-carcinogenic, anti-inflammatory and antiviral properties, yet similarly to many promising APIs, its in vivo administration is complicated by low aqueous solubility and unfavourable pharmacokinetics.
Michał Sowa, Katarzyna Ślepokura, Ewa Matczak-Jon   +2 more
openaire   +1 more source

A Comprehensive Insight on Pharmaceutical Co-crystals for Improvement of Aqueous Solubility

Current Drug Targets, 2023
Arun Nanda
exaly  

An investigation into solubility and dissolution improvement of alectinib hydrochloride as a third-generation amorphous solid dispersion

Journal of Drug Delivery Science and Technology, 2023
Kiran Dubey, amita Joshi, Sumit Kumar Saha   +2 more
exaly  

Improved Method for Microencapsulation of Soluble Pharmaceuticals

Journal of Pharmaceutical Sciences, 1975
J W, McGinity, A B, Combs, A N, Martin
openaire   +2 more sources

Improving solubility

Environmental Science & Technology, 1995
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Food proteins: Solubility & thermal stability improvement techniques

Food Chemistry Advances, 2022
Soleiman Abbasi
exaly  

Improvement of chitosan water solubility by fumaric acid modification

Materials Letters, 2022
Pradeep Kumar Panda, Jen-Ming Yang, Yen-Hsiang Chang   +2 more
exaly