Results 41 to 50 of about 2,906,554 (204)

Effect of a mixture of caffeine and nicotinamide on the solubility of vitamin (B2) in aqueous solution [PDF]

, 2006
The effect of caffeine (CAF) and nicotinamide (NMD) on the solubility of a vitamin B2 derivative (FMN) has been evaluated for mixtures containing either a single hydrotrope (CAF or NMD) or the two hydrotropes simultaneously.
Davies, David B., Hernandez Santiago, A.A., Evstigneev, V.P., Evstigneev, M.P.   +3 more
core   +1 more source

Improving the solubility of dexlansoprazole by cocrystallization with isonicotinamide

European Journal of Pharmaceutical Sciences, 2016
Cocrystallization of an active pharmaceutical ingredient (API) with a cocrystal former (co-former) is widely used to tailor the physicochemical properties of parent APIs. For proton-pump inhibitors (PPIs), the isolation of cocrystals has not been widely investigated.
Jianhui Li, Lianyan Wang, Yue Qi Ye, Xue Fu, Qinghua Ren, Hailu Zhang, Zongwu Deng   +6 more
openaire   +2 more sources

Therapeutic Liquid Formulations Based on Low Transition Temperature Mixtures for the Incorporation of Anti-Inflammatory Drugs

Pharmaceutics, 2021
Most nonsteroidal anti-inflammatory drugs (NSAIDs) present poor aqueous solubility, impairing their efficiency in physiological media. In this context, Low Transition Temperature Mixtures (LTTMs) are a promising platform to overcome drugs’ poor ...
Ana Roda, Alexandre Paiva, Ana Rita C. Duarte   +2 more
doaj   +1 more source

Improvement of Solubility and Dissolution of Niclosamide using Metal Organic Framework 5 (MOF-5)

Iraqi Journal of Pharmaceutical Sciences
Metal-organic frameworks-5 (MOF-5) were explored for enhancement of the solubility and dissolution of the drug niclosamide (NIC). MOF-5 was synthesized by solvothermal method and NIC was loaded into it (NIC@MOF-5).
Hayder Yahya Mansoor Al-Jarsha, Mowafaq M. Ghareeb   +1 more
doaj   +1 more source

Solubility examination of palm kernel oil in supercritical CO2 and its correlation with solvent density based model [PDF]

, 2012
Application of supercritical carbon dioxide (SC-CO2) to vegetable oil extraction became an attractive technique due to its high solubility, short extraction time and simple purification.
Priyo , Atmaji, Didi , Dwi Anggoro, Wahyu , Bahari Setianto   +2 more
core   +4 more sources

The Prodrug Approach: A Successful Tool for Improving Drug Solubility

Molecules, 2015
Prodrug design is a widely known molecular modification strategy that aims to optimize the physicochemical and pharmacological properties of drugs to improve their solubility and pharmacokinetic features and decrease their toxicity.
Daniela Hartmann Jornada, Guilherme Felipe dos Santos Fernandes, Diego Eidy Chiba, Thais Regina Ferreira de Melo, Jean Leandro dos Santos, Man Chin Chung   +5 more
doaj   +1 more source

Development of self-nanoemulsifying drug delivery systems for the enhancement of solubility and oral bioavailability of fenofibrate, a poorly water-soluble drug

International Journal of Nanomedicine, 2016
Kazi Mohsin,1 Rayan Alamri,1 Ajaz Ahmad,2 Mohammad Raish,3 Fars K Alanazi,1 Muhammad Delwar Hussain4 1Kayyali Chair for Pharmaceutical Industry, Department of Pharmaceutics, 2Department of Clinical Pharmacy, 3Department of Pharmaceutics, College of ...
Moshin K, Alamri R, Ahmad A, Raish M, Alanazi FK, Hussain MD   +5 more
doaj  

Preparation and Characterization of Novel Pharmaceutical Co-Crystals: Ticagrelor with Nicotinamide

Crystals, 2018
Two new co-crystals, Ticagrelor with Nicotinamide, have been prepared with improved solubility. Because Ticalegor has a poor solubility and dissolution rate, a novel co-crystallization method with structurally homogenous crystalline material, an active ...
Muhammad Inam, Jiajia Wu, Jie Shen, Chi Uyen Phan, Guping Tang, Xiurong Hu   +5 more
doaj   +1 more source

IUPAC-NIST solubility data series. 81. Hydrocarbons with water and seawater - Revised and updated. Part 11. C13-C36 hydrocarbons with water [PDF]

, 2005
The mutual solubilities and related liquid-liquid equilibria of C 13-C36 hydrocarbons with water are exhaustively and critically reviewed. Reports of experimental determination of solubility in 56 chemically distinct binary systems that appeared in the ...
Owczarek, I., Zofia Maczynska, Costa Tsonopoulos, Iwona Owczarek, Huyskens, P.L., Haulait-Pirson, M-C., Kapuku, F., Marie-Claire Haulait-Pirson, Glenn T. Hefter, Colin L. Young, Barbara Wisniewska-Goclowska, David G. Shaw, Marian Goral, Maczynska, Z., Hefter, G.T., Young, C.L., Adam Skrzecz, Blazej, K., F. Kapuku, Skrzecz, A., Maczynski, A., Krystyna Blazej, Wisniewska-Goclowska, B., Tsonopoulos, C., Szafranski, A., Andrzej Szafranski, Goral, M., Shaw, D.G., Andrzej Maczynski   +28 more
core   +1 more source

Solubility and Dissolution Rate Enhancement of Bilastine by Solid Dispersion Technique

Iraqi Journal of Pharmaceutical Sciences
Bilastine (BLS) is non-sedating new-brand H1 antihistamine that has selective peripheral effects, the drug has a problem of an insufficient aqueous solubility and accordingly low dissolution rate, and low bioavailability. Solid dispersion (SD) is one of
Mariam Hamid Ali, Kawther Khalid Ahmed
doaj   +1 more source