Results 21 to 30 of about 2,906,554 (204)
Pharmaceutics, 2018 The objective of the study was to develop baicalin loaded liquid self-nanoemulsifying drug delivery systems (BSNEDDS) and to characterize them by physicochemical methods in order to optimize the composition and quality attributes. Atomic force microscopy
Géza Jakab +5 more
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A STUDY ON THE EFFECT OF GERMINATION ON THE PROTEIN OF SOME OILSEEDS [PDF]
Journal of Soil Sciences and Agricultural Engineering, 2000 Soybean, sunflower and cottonseed kernels were germinated in different aqueous solutions for 12, 24 and 48 hours. The germinating solutions included: sodium carbonate-sodium bicarbonate buffer (pH 9.4), 2% ammonium carbonate, 2% ammonium carbonate ...
Fakhriya Taha, Samira Mohamed,
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Investigating the Effect of Basic Amino Acids and Glucosamine on the Solubility of Ibuprofen and Piroxicam [PDF]
Advanced Pharmaceutical Bulletin, 2023 Purpose: Poor aqueous solubility hampers the development of several compounds as pharmacological agents. Hence, preparing novel formulations with augmented absorption is a challenge in pharmaceutical industries. In this paper, we have examined the effect
Hadi Valizadeh +5 more
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The boehmite ‘solubility gap’ [PDF]
, 2010 Boehmite, rather than gibbsite, precipitation has been proposed in the literature as a potential energy-saving modification of the Bayer process for the production of alumina. Previous experimental studies have reported that true equilibrium solubilities
Erich Königsberger +5 more
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Uniting cheminformatics and chemical theory to predict the intrinsic aqueous solubility of crystalline druglike molecules [PDF]
, 2014 We present four models of solution free-energy prediction for druglike molecules utilizing cheminformatics descriptors and theoretically calculated thermodynamic values.
van Mourik, Tanja +17 more
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Heliyon, 2023 BCS class II drugs exhibit low aqueous solubility and high permeability. Such drugs often have an incomplete or erratic absorption profile. This study aimed to predict the effects of β-cyclodextrin (βCD) and different hydrophilic polymers (poloxamer 188 (
Waqas Haider Khan +10 more
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Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption. [PDF]
, 2015 Oral absorption depends on many physiological, physiochemical and formulation factors. Two important properties that govern oral absorption are in vitro permeability and solubility, which are commonly used as indicators of human intestinal absorption ...
Newby, Danielle +6 more
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Zein as an Effective Carrier for Hesperidin Delivery Systems with Improved Prebiotic Potential
Molecules, 2023 Hesperidin is a polyphenol derived from citrus fruits that has a broad potential for biological activity and the ability to positively modify the intestinal microbiome. However, its activity is limited by its low solubility and, thus, its bioavailability—
Szymon Sip +4 more
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Crystals, 2022 Crystal engineering and, more specifically, the development of multicomponent materials has become an effective technique to rationally modify important physicochemical properties of solids, such as solubility and thermal stability.
Cristóbal Verdugo-Escamilla +4 more
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An evaluation of thermodynamic models for the prediction of drug and drug-like molecule solubility in organic solvents [PDF]
, 2011 Prediction of solubility of active pharmaceutical ingredients (API) in different solvents is one of the main issue for crystallization process design. Experimental determination is not always possible because of the small amount of product available in ...
Béatrice Biscans +5 more
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