Current Techniques of Water Solubility Improvement for Antioxidant Compounds and Their Correlation with Its Activity: Molecular Pharmaceutics [PDF]
Antioxidants, 2023 The aqueous solubility of a drug is important in the oral formulation because the drug can be absorbed from intestinal sites after being dissolved in the gastrointestinal fluid, leading to its bioavailability.
Arif Budiman +2 more
doaj +4 more sources
Solubility Improvement of Benexate through Salt Formation Using Artificial Sweetener [PDF]
Pharmaceutics, 2018 Benexate, a drug used clinically as a defensive type anti-ulcer agent, has poor solubility and a bitter taste. To improve its solubility, a crystal engineering approach was proposed with the formation of novel salts using an artificial sweetener as a ...
Okky Dwichandra Putra +6 more
doaj +4 more sources
Highly Responsive Chitosan-Co-Poly (MAA) Nanomatrices through Cross-Linking Polymerization for Solubility Improvement [PDF]
Gels, 2022 In this study, we report the highly responsive chitosan-based chemically cross-linked nanomatrices, a nano-version of hydrogels developed through modified polymerization reaction for solubility improvement of poorly soluble drug simvastatin.
Anam Saleem +5 more
doaj +2 more sources
Solubility improvement of atorvastatin using deep eutectic solvents [PDF]
Journal of Advanced Pharmaceutical Technology & ResearchDeep eutectic solvents (DESs) in pharmaceutical investigations are still largely unknown in terms of safety, environmental acceptability, and practical use.
Yoga Windhu Wardhana +2 more
doaj +2 more sources
Co-amorphization for solubility and dissolution rate improvement: the case of low-crystallization-tendency drugs [PDF]
Saudi Pharmaceutical JournalPoor aqueous solubility and limited oral bioavailability remain major challenges in drug development. Although amorphous forms can improve solubility and dissolution, their physical stability is often compromised by recrystallization.
Arif Budiman +10 more
doaj +2 more sources
Complexation: An Interesting Pathway for Combining Two APIs at the Solid State
Pharmaceutics, 2022 Combining different drugs into a single crystal form is one of the current challenges in crystal engineering, with the number of reported multi-drug solid forms remaining limited.
Fucheng Leng +3 more
doaj +1 more source
Food proteins: Solubility & thermal stability improvement techniques
Food Chemistry Advances, 2022 Proteins, as the major structural component, play important roles in food systems because of possessing bioactive nature, and valuable nutritional and functional characteristics.
Negin Yousefi, Soleiman Abbasi
doaj +1 more source
Students' Knowledge of Solubility Topics through The Cooperative Learning STAD Type
Jurnal Pendidikan Sains Universitas Muhammadiyah Semarang, 2022 The topic of solubility is included in the chemistry subject matter that is considered difficult by students. This study aims to identify differences in knowledge improvement between the experimental class using the cooperative learning model STAD ...
Ismi Nurlatifah +2 more
doaj +1 more source
Pharmaceutics, 2020 Apigenin (APG) is a very well-known flavonoid for its anti-inflammatory and anticancer properties. The purpose of this study is to improve the solubility and bioavailability of APG using a stable bioactive self-nanoemulsifying drug delivery system (Bio ...
Mohsin Kazi +8 more
doaj +1 more source
Pharmaceutics, 2020 Curcumin (CUR) is an attractive polyphenol for its anti-inflammatory, antibacterial, antioxidant, and anticancer properties. Poor solubility in water and sensitivity against sunlight are the most challenging characteristics in the development of CUR for ...
Mohsin Kazi +5 more
doaj +1 more source