Results 161 to 170 of about 82,173 (258)

A Wagner–Meerwein‐Like Rearrangement Generates a Vinyl Group in the Biosynthesis of the Polychlorinated Lipopeptides Fischerazoles

open access: yesAngewandte Chemie, EarlyView.
The fischerazoles, unusual cyanobacterial chlorinated lipopeptides are reported. During their biosynthesis, a linear fatty acyl‐acyl carrier protein (ACP) precursor is rearranged through the action of the S‐adenosyl‐methionine (SAM)‐dependent methyltransferase FshF, to generate a pendant vinyl group.
Sandra A. C. Figueiredo   +8 more
wiley   +2 more sources

Rediscovering Sodium Ionophores as Selective Agents for Lithium Recognition and Extraction

open access: yesAngewandte Chemie, EarlyView.
Long‐classified sodium ionophores unexpectedly prefer lithium and act as efficient extractants in solid–liquid extraction (SLE). Readily prepared from catechol and haloacetamides, these hosts recover hydrated LiCl from multicomponent salt mixtures via a hydration‐assisted O···Li+ binding mode, enabling scalable lithium separation with Li/Na, Li/K, and ...
Jakub Narodowiec   +6 more
wiley   +2 more sources

Large‐Diameter DNA‐Scaffolded Nanopores Enabled by Loosely Packed Peptides for Single‐Molecule Sensing

open access: yesAngewandte Chemie, EarlyView.
A nanopore composed of transmembrane peptides and a DNA scaffold that assists peptide assembly was constructed. By employing peptides containing the unnatural amino acid 2‐aminoisobutyric acid (Aib), which promotes loose packing between helices, a large‐diameter nanopore was achieved.
Zugui Peng   +3 more
wiley   +2 more sources

Selective Nitrate Transmembrane Transport Through Adaptive Weak C─H Bonding Cyanostilbene Water Channels

open access: yesAngewandte Chemie, EarlyView.
Here we demonstrate that weak HB CH donor cyanostilbenes promote water/ion transport through their ability to form less‐ordered transient water channels within the lipid bilayer with increased water permeability and NO3−/ Cl− selectivity. ABSTRACT Transmembrane water transport strongly depends on how dynamic, translocating water clusters are stabilized
Ioan Stroia   +6 more
wiley   +2 more sources

Fungal Transformation and Oxalate-Mediated Mineralization of Heavy Metal Oxides by <i>Aspergillus aculeatus</i>. [PDF]

open access: yesJ Xenobiot
Sawangchart T   +6 more
europepmc   +1 more source

Harnessing the Reactivity of Sulfinate Salts With Cystine: An Umpolung Approach to Residue‐Specific Peptide Modification

open access: yesAngewandte Chemie, EarlyView.
While cysteine is widely employed as a nucleophilic handle for peptide modification, the electrophilicity of the oxidized form, cystine, is rarely exploited. This study describes a mild, photochemical coupling of sulfinate salts with peptide disulfides.
Joshua M. Hammond   +7 more
wiley   +2 more sources

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