Advanced Science, EarlyView.This study investigates the impact of various post‐processing methods (filtration, sonication, dialysis, and heating) on lipid nanoparticles produced using microfluidics. The nanoparticles are designed for efficient delivery of miRNA into cells. The work highlights how processing conditions influence nanoparticle stability and quality, providing ...
Alicja Kosik‐Kozioł +8 more
wiley +1 more source
Single-cell western blotting of cytoplasmic cytokeratin 8 proteoforms.
AnalystFomitcheva Khartchenko A +2 more
europepmc +1 more source
Characterization of lipid solubilization, bicelle formation, and magnetic-alignment induced by saponins. [PDF]
J Colloid Interface SciMcCalpin SD +3 more
europepmc +1 more source
Advanced Science, EarlyView.PEA nanoenzymes are assembled from L‐arginine and EGCG. The nitrogen element in arginine enhances the thermodynamic feasibility of H2O2 production through PEA's oxygen reduction catalysis, enabling nitrogen‐dependent H2O2 release. Intradermal delivery of PEA via microneedles promotes efficient H2O2 synthesis, thereby stimulating regrowth in telogen ...
Yifei Wang +7 more
wiley +1 more source
Enhanced nitrogen load improved soil phosphorus availability by regulating P-cycling microbial genes in a typical subtropical estuary (Min River), Southeast China. [PDF]
Environ MicrobiomeWu H, Sun Z, Chen B, Hu X, Li Y.
europepmc +1 more source
Advanced Science, EarlyView.Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács +9 more
wiley +1 more source
Capric Acid-Based Therapeutic Deep Eutectic Systems: A Focused Review Within the Framework of Deep Eutectic Solvents. [PDF]
Pharmaceuticals (Basel)Al-Akayleh F +3 more
europepmc +1 more source
Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders
Advanced Science, EarlyView.Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li +7 more
wiley +1 more source
Determination of the cytotoxic effects of parasporal proteins in native Bacillus thuringiensis isolates on various cancer cell lines and investigation of the apoptotic, synergistic, and angiogenic potency of the isolate Bt 5.4. [PDF]
BMC BiotechnolKesik Oktay M, Şahin B, Güneş H.
europepmc +1 more source
Advanced Science, EarlyView.We report, for the first time, an external electric field (EEF) strategy to achieve co‐aggregation of conjugated polymer blends (i.e., poly(3‐butylthiophene) and poly[3,3'''‐dialkyl‐quaterthiophene]s) in the solution and thus their cocrystals in thin films, demonstrating cocrystal‐improved charge mobilities due to the synergy of two components ...
Yanan Guo, Hao Zheng, Juan Peng
wiley +1 more source