AC1497 is an effective dual inhibitor of malate dehydrogenase 1 and 2 targeting cancer metabolism. However, its poor aqueous solubility results in low bioavailability, limiting its clinical development.
Kshitis Chandra Baral +7 more
doaj +1 more source
Structural characterization of biocompatible reverse micelles using Small-Angle X-ray Scattering, 31P Nuclear Magnetic Resonance, and Fluorescence Spectroscopy [PDF]
The most critical problem regarding the use of reverse micelles (RMs) in several fields is the toxicity of their partial components. In this sense, many efforts have been made to characterize nontoxic RM formulations on the basis of biological ...
Ceolín, Marcelo +4 more
core +1 more source
Preparation of nuclear matrices from cultured cells: subfractionation of nuclei in situ [PDF]
Analyses of the different structural systems of the nucleus and the proteins associated with them pose many problems. Because these systems are largely overlapping, in situ localization studies that preserve the in vivo location of proteins and cellular ...
Deppert, Wolfgang, Staufenbiel, Matthias
core +2 more sources
Endophyte-Promoted Phosphorus Solubilization in Populus
Phosphorus is one of the essential nutrients for plant growth, but it may be relatively unavailable to plants because of its chemistry. In soil, the majority of phosphorus is present in the form of a phosphate, usually as metal complexes making it bound ...
Tamas Varga +14 more
doaj +1 more source
Extraction of humic acid by coacervate: Investigation of direct and back processes [PDF]
The two aqueous phases extraction process is widely used in environmental clean up of industrial effluents and fine chemical products for their reuse.
Derriche, Zoubir +4 more
core +3 more sources
Cooperativity in micellar solubilization [PDF]
Enhanced surfactant association by solutes drives cooperative solubilization according to the universal statistical thermodynamic theory.
Seishi Shimizu, Nobuyuki Matubayasi
openaire +4 more sources
Hydrophobically modified polyelectrolytes as potential drugs reservoirs of n-alkyl-nitroimidazoles [PDF]
Indexación: ScieloThe solubilization of three commercial drugs (ornindazole, metronidazole and tinidazole) and model compounds (N-alkyl-2-methyl-4-nitroimidazoles) on aggregates formed by anionic polyelectrolytes, carrying alkyl side chains of different ...
Acevedo, Betsabé +3 more
core +1 more source
Density and surface tension of aqueous solutions of adjuvants used for tank-mixes with pesticides
Adjuvants are surface active agents that are added to pesticide formulations or tank-mix to facilitate the mixing, application, or efficacy of these products. Addition of adjuvants changes the physico-chemical properties of spray liquid. In this work, we
J. Janků +4 more
doaj +1 more source
This study investigated the solubilization capabilities of rhamnolipids biosurfactant and synthetic surfactant mixtures for the application of a mixed surfactant in surfactant-enhanced remediation.
Jianfei Liu, Yuru Wang, Huifang Li
doaj +1 more source
Rcf1 and Rcf2, Members of the Hypoxia-induced Gene 1 Protein Family, Are Critical Components of the Mitochondrial Cytochrome bc1-cytochrome Oxidase Supercomplex [PDF]
We report that Rcf1 (formerly Aim31), a member of the conserved hypoxia-induced gene 1 (Hig1) protein family, represents a novel component of the yeast cytochrome bc1-cytochrome c oxidase (COX) supercomplex.
Furness, Andrew +4 more
core +2 more sources

