Results 41 to 50 of about 102,687 (293)

Fungal rock phosphate solubilization using sugarcane bagasse [PDF]

, 2012
The effects of different doses of rock phosphate (RP), sucrose, and (NH4)2SO4 on the solubilization of RP from Araxá and Catalão (Brazil) by Aspergillus niger, Penicillium canescens, Eupenicillium ludwigii, and Penicillium islandicum were evaluated in a ...
Costa, Maurício D., Ribeiro Júnior, José Ivo, Silva, Ivo R., Pereira, Olinto L., Mendes, Gilberto O., Dias, Carla S.   +5 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Improvement in Solubility–Permeability Interplay of Psoralens from Brosimum gaudichaudii Plant Extract upon Complexation with Hydroxypropyl-β-cyclodextrin

Molecules, 2022
Psoralen (PSO) and 5-methoxypsoralen (5-MOP) are widely used drugs in oral photochemotherapy against vitiligo and major bioactive components of root bark extract of Brosimum gaudichaudii Trécul (EBGT), previously standardized by LC-MS.
Rúbia Darc Machado, Júlio C. G. Silva, Luís A. D. Silva, Gerlon de A. R. Oliveira, Luciano M. Lião, Eliana M. Lima, Mariana C. de Morais, Edemilson C. da Conceição, Kênnia R. Rezende   +8 more
doaj   +1 more source

Solubilization By Polysoaps

, 1994
The aqueous solubilization power of several series of micellar homopolymers and copolymers (''polysoaps'') is investigated. Using five insoluble or poorly water-soluble dyes, comparisons of the capacities are made with respect to the influence of ...
Laschewsky, A., Anton, P.
core   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Mechanochemical solid acid/base reactions for obtaining biologically active preparations and extracting plant materials

Green Chemistry Letters and Reviews, 2017
Mechanochemically assisted extraction involves the mechanical treatment of powder mixtures of plant materials and convenient reagents in special mill-activators to solubilize the biologically active substances.
Oleg I. Lomovsky, Igor O. Lomovskiy, Denis V. Orlov   +2 more
doaj   +1 more source

Revisiting the Solubility–Permeability Relationship with Hydrophobic Drug Umifenovir in Pluronic Solutions: Impact of pH and Co-Solvent

Pharmaceutics, 2023
This study describes the influence of pluronic F-127 (F-127) and ethanol (EtOH) on the solubility of umifenovir (UMF) in buffer solutions of pH 2.0 and pH 7.4, and its permeability through cellulose membranes. A 44.4-fold greater UMF solubility in acidic
Tatyana Volkova, Olga Simonova, German Perlovich   +2 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Solubilization capacity and solubilization efficiency of tea seed oil.

, 2015
The solubilization capacity of tea seed oil (amount of tea seed oil per preparation) (×), and solubilization efficiency (amount of tea seed oil normalized to the amount of oil, ethanol, and surfactant) (∆) were plotted against the aqueous phase content ...
Fei Que (474313), Xiaowei Dong (742675), Lingli Deng (742672), Guangwei Xu (742674), Hewen Wei (742673), Hui Zhang (7197)   +5 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source