Analysis of the molecular mobility of collagen and elastin in safe, atheromatous and aneurysmal aortas [PDF]
, 2012 Aim of the study : In this study, we propose to use a thermal technique, Differential Scanning Calorimetry (DSC) to follow the evolution of elastin and collagen in safe and pathological cardiovascular tissues.
Dandurand, Jany +7 more
core +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Formulation of Green PGD Polymeric Nanoparticles of Curcumin: Physicochemical Characterization, Stability testing and Docking Study Targeting BTK [PDF]
BIO Web of ConferencesPolymers structured as nanoparticles for encapsulating the hydrophobic drugs is a strategy considered as a useful way to improve drug absorption and lower off-target activity.
Ahmed Rania H. H. +4 more
doaj +1 more source
Speciation and Mobilization of Toxic Heavy Metal Ions by Methanogenic Bacteria [PDF]
, 1993 HWRIC Project HWR 92 ...
Conver, Shawn +5 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2012 The solubilization capacity of water / oil / AOT (sodium bis(2 ethylhexyl)sulfosuccinate) microemulsions was studied as a function of a fourth component added in the system. Addition of cosurfactant modifies the water solubility and the properties of the
SANDU PERETZ +2 more
doaj
Production of protein extracts from Swedish red, green, and brown seaweeds, Porphyra umbilicalis Kützing, Ulva lactuca Linnaeus, and Saccharina latissima (Linnaeus) J. V. Lamouroux using three different methods [PDF]
, 2018 peer-reviewedThe demand for vegetable proteins increases globally and seaweeds are considered novel and promising protein sources. However, the tough polysaccharide-rich cell walls and the abundance of polyphenols reduce the extractability and ...
Carlsson, Nils-Gunnar +5 more
core +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
PERSPECTIVE OF INNOVATION DRUG FORMULATION WITH DARUNAVIR ETHANOLAT
Разработка и регистрация лекарственных средств, 2019 Article shows the results of development and technological issues of darunavir ethanolate in capsule form. Soluplus was used to increase the biopharmaceutical characteristics of current drug formulation.
S. A. Zolotov +3 more
doaj
Cloud point extraction of phenol and benzyl alcohol from aqueous stream [PDF]
, 2006 Two-aqueous phase extraction of phenol and benzyl alcohol as a solute from their aqueous solutions was investigated using polyethoxylated alcohols (CiEj) as a biodegradable non-ionic surfactant.
Canselier, Jean-Paul +2 more
core +2 more sources