Functional Selectivity of Allosteric Interactions within GPCR oligomers: the Dopamine D1-D3 Receptor Heterotetramer [PDF]
The dopamine D1 receptor-D3 receptor (D1R-D3R) heteromer is being considered as a potential therapeutic target for neuropsychiatric disorders. Previous studies suggested that this heteromer could be involved in the ability of D3R agonists to potentiate ...
Antoni Cortés +16 more
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Editorial: Advances in cAMP signaling research: basic and translational aspects
Muhammad Aslam +3 more
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Soluble Adenylyl Cyclase Activity Is Necessary for Retinal Ganglion Cell Survival and Axon Growth [PDF]
Raul G. Corredor +5 more
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Roles of lipid raft in the regulation of sperm motility in the ascidian Ciona intestinalis [PDF]
Thesis (Ph. D. in Science)--University of Tsukuba, (A), no. 5938, 2011.11.30Includes bibliographical references (p.
朱 麗紅
core
Corticotropin-releasing factor receptors couple to multiple g-proteins to activate diverse intracellular signaling pathways in mouse hippocampus: role in neuronal excitability and associative learning [PDF]
Corticotropin-releasing factor (CRF) exerts a key neuroregulatory control on stress responses in various regions of the mammalian brain, including the hippocampus.
Blank, T. (Thomas) +5 more
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Dopamine D1, D2 and mu-opioid receptors are co-expressed with adenylyl cyclase 5 and phosphodiesterase 7B mRNAs in striatal rat cells [PDF]
El pdf es la versión post-print.Intracellular cAMP levels are regulated by cAMP synthesis and degradation rate. Nine isoforms of cAMP-synthesizing enzymes called adenylyl-cyclases (ACs) and eleven phosphodiesterases (PDEs) that degrade cyclic nucleotides
Griesshammer, Martin +2 more
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Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate [PDF]
S. Kleinboelting +7 more
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A Soluble C1b Protein and Its Regulation of Soluble Type 7 Adenylyl Cyclase
Adenylyl cyclase (AC) is a prototypical cell-signaling molecule expressed in virtually all organisms from bacteria to man. While C1b, a poorly conserved region within mammalian AC, has been implicated in numerous isoform-specific regulatory properties, no one has purified the C1b region as a functional protein to homogeneity in order to study its role ...
Jeff A, Beeler +5 more
openaire +2 more sources
Regulation of Anterior Chamber Drainage by Bicarbonate-sensitive Soluble Adenylyl Cyclase in the Ciliary Body [PDF]
Yong S. Lee +6 more
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Soluble adenylyl cyclase contributes to imiquimod‐mediated inflammation and is a potential therapeutic target in psoriasis [PDF]
Jaewon You +12 more
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