Results 141 to 150 of about 19,134 (215)

Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate [PDF]

, 2014
S. Kleinboelting, Ana Díaz, S. Moniot, Joop van den Heuvel, Michael Weyand, Lonny R. Levin, Jochen Buck, Clemens Steegborn   +7 more
openalex   +1 more source

Proton Fall or Bicarbonate Rise: Glycolytic Rate In Mouse Astrocytes Is Paved By Intracellular Alkalinization [PDF]

, 2016
Glycolysis is the primary step for major energy production in the cell. There is strong evidence suggesting that glucose consumption and rate of glycolysis are highly modulated by cytosolic pH/[H(+)], but those can also be stimulated by an increase in ...
Deitmer, JW, Ruminot, I, Schmälzle, J, Theparambil, SM, Weber, T   +4 more
core   +1 more source

Regulation of Anterior Chamber Drainage by Bicarbonate-sensitive Soluble Adenylyl Cyclase in the Ciliary Body [PDF]

, 2011
Yong S. Lee, Martín Tresguerres, Kenneth C. Hess, Lihua Y. Marmorstein, Lonny R. Levin, Jochen Buck, Alan D. Marmorstein   +6 more
openalex   +1 more source

Nonpigmented Ciliary Epithelial Cells Respond to Acetazolamide by a Soluble Adenylyl Cyclase Mechanism [PDF]

, 2013
Mohammad Shahidullah, Amritlal Mandal, Guojun Wei, Lonny R. Levin, Jochen Buck, Nicholas A. Delamere   +5 more
openalex   +1 more source

Soluble adenylyl cyclase [PDF]

, 2011
Thomas Kolodecik and Fred S. Gorelick
openalex   +1 more source

Soluble adenylyl cyclase contributes to imiquimod‐mediated inflammation and is a potential therapeutic target in psoriasis [PDF]

, 2023
Jaewon You, Michael Reilly, Mahmoud Eljalby, Rohan Bareja, Maftuna Yusupova, Nikki S. Vyas, Jakyung Bang, Wanhong Ding, Garrett Desman, Lloyd Miller, Olivier Elemento, Richard D. Granstein, Jonathan H. Zippin   +12 more
openalex   +1 more source

Using a Robust and Sensitive GFP-Based cGMP Sensor for Real-Time Imaging in Intact Caenorhabditis elegans. [PDF]

, 2019
cGMP plays a role in sensory signaling and plasticity by regulating ion channels, phosphodiesterases, and kinases. Studies that primarily used genetic and biochemical tools suggest that cGMP is spatiotemporally regulated in multiple sensory modalities ...
Ali, Nebat, Andersen, Kristine, Barsi-Rhyne, Benjamin, Brueggemann, Chantal, Costa, Wagner Steuer, Ferkey, Denise M, Futey, Mary, Gottschalk, Alexander, Hamilton, O Scott, Hill, Tyler, Krzyzanowski, Michelle C, L'Etoile, Noelle, Li, Joy, Mitchell, Jordan, Nagpal, Jatin, Schneider, Martin W, Sengupta, Piali, Shankar, Raakhee, Tran, Alan, VanHoven, Miri, Varshney, Aruna, Woldemariam, Sarah, Yu, Yanxun V   +22 more
core  

Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration [PDF]

, 2015
Richard L. Watson, Jochen Buck, Lonny R. Levin, Ryan C. Winger, Jing Wang, Hisashi Arase, William A. Müller   +6 more
openalex   +1 more source

Adverse effects of Δ9-tetrahydrocannabinol on neuronal bioenergetics during postnatal development

JCI Insight, 2020
Ongoing societal changes in views on the medical and recreational roles of cannabis increased the use of concentrated plant extracts with a Δ9-tetrahydrocannabinol (THC) content of more than 90%.
Johannes Beiersdorf, Zsofia Hevesi, Daniela Calvigioni, Jakob Pyszkowski, Roman Romanov, Edit Szodorai, Gert Lubec, Sally Shirran, Catherine H. Botting, Siegfried Kasper, Geoffrey W. Guy, Roy Gray, Vincenzo Di Marzo, Tibor Harkany, Erik Keimpema   +14 more
doaj   +1 more source

Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates. [PDF]

J Med Chem, 2022
Miller M, Rossetti T, Ferreira J, Ghanem L, Balbach M, Kaur N, Levin LR, Buck J, Kehr M, Coquille S, van den Heuvel J, Steegborn C, Fushimi M, Finkin-Groner E, Myers RW, Kargman S, Liverton NJ, Huggins DJ, Meinke PT.   +18 more
europepmc   +1 more source