Results 141 to 150 of about 19,255 (216)

Nonpigmented Ciliary Epithelial Cells Respond to Acetazolamide by a Soluble Adenylyl Cyclase Mechanism [PDF]

, 2013
Mohammad Shahidullah, Amritlal Mandal, Guojun Wei, Lonny R. Levin, Jochen Buck, Nicholas A. Delamere   +5 more
openalex   +1 more source

Soluble adenylyl cyclase [PDF]

, 2011
Thomas Kolodecik and Fred S. Gorelick
openalex   +1 more source

Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration [PDF]

, 2015
Richard L. Watson, Jochen Buck, Lonny R. Levin, Ryan C. Winger, Jing Wang, Hisashi Arase, William A. Müller   +6 more
openalex   +1 more source

Using a Robust and Sensitive GFP-Based cGMP Sensor for Real-Time Imaging in Intact Caenorhabditis elegans. [PDF]

, 2019
cGMP plays a role in sensory signaling and plasticity by regulating ion channels, phosphodiesterases, and kinases. Studies that primarily used genetic and biochemical tools suggest that cGMP is spatiotemporally regulated in multiple sensory modalities ...
Ali, Nebat, Andersen, Kristine, Barsi-Rhyne, Benjamin, Brueggemann, Chantal, Costa, Wagner Steuer, Ferkey, Denise M, Futey, Mary, Gottschalk, Alexander, Hamilton, O Scott, Hill, Tyler, Krzyzanowski, Michelle C, L'Etoile, Noelle, Li, Joy, Mitchell, Jordan, Nagpal, Jatin, Schneider, Martin W, Sengupta, Piali, Shankar, Raakhee, Tran, Alan, VanHoven, Miri, Varshney, Aruna, Woldemariam, Sarah, Yu, Yanxun V   +22 more
core  

Adverse effects of Δ9-tetrahydrocannabinol on neuronal bioenergetics during postnatal development

JCI Insight, 2020
Ongoing societal changes in views on the medical and recreational roles of cannabis increased the use of concentrated plant extracts with a Δ9-tetrahydrocannabinol (THC) content of more than 90%.
Johannes Beiersdorf, Zsofia Hevesi, Daniela Calvigioni, Jakob Pyszkowski, Roman Romanov, Edit Szodorai, Gert Lubec, Sally Shirran, Catherine H. Botting, Siegfried Kasper, Geoffrey W. Guy, Roy Gray, Vincenzo Di Marzo, Tibor Harkany, Erik Keimpema   +14 more
doaj   +1 more source

4805GLP-1(28–36) prevents ischemic cardiac injury by modulating metabolism and activating soluble adenylyl cyclase in coronary vascular cells [PDF]

, 2017
M. Ahsan Siraj, Dhanwantee Mundil, Talat Afroze, Liu Ying, Michael B. Wheeler, G. Keller, Mansoor Husain   +6 more
openalex   +1 more source

Kinetic Properties of “Soluble” Adenylyl Cyclase [PDF]

Journal of Biological Chemistry, 2003
Tatiana N. Litvin, Margarita Kamenetsky, Alla Zarifyan, Jochen Buck, Lonny R. Levin   +4 more
openaire   +1 more source

Administration of Bicarbonate Protects Mitochondria, Rescues Retinal Ganglion Cells, and Ameliorates Visual Dysfunction Caused by Oxidative Stress

Antioxidants
Oxidative stress is a key factor causing mitochondrial dysfunction and retinal ganglion cell (RGC) death in glaucomatous neurodegeneration. The cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA) signaling pathway is involved in mitochondrial ...
Tonking Bastola, Guy A. Perkins, Viet Anh Nguyen Huu, Saeyeon Ju, Keun-Young Kim, Ziyao Shen, Dorota Skowronska-Krawczyk, Robert N. Weinreb, Won-Kyu Ju   +8 more
doaj   +1 more source

Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates. [PDF]

J Med Chem, 2022
Miller M, Rossetti T, Ferreira J, Ghanem L, Balbach M, Kaur N, Levin LR, Buck J, Kehr M, Coquille S, van den Heuvel J, Steegborn C, Fushimi M, Finkin-Groner E, Myers RW, Kargman S, Liverton NJ, Huggins DJ, Meinke PT.   +18 more
europepmc   +1 more source

Soluble adenylyl cyclase, the cell-autonomous member of the family

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Soluble adenylyl cyclase (sAC) is the evolutionarily most ancient of a set of 10 adenylyl cyclases (Adcys). While Adcy1 to Adcy9 are cAMP-producing enzymes that are activated by G-protein coupled receptors (GPCRs), Adcy10 (sAC) is an intracellular adenylyl cyclase.
Hang Lam, Li, Simei, Go, Jung-Chin, Chang, Arthur, Verhoeven, Ronald Oude, Elferink   +4 more
openaire   +2 more sources