Results 151 to 160 of about 19,134 (215)

4805GLP-1(28–36) prevents ischemic cardiac injury by modulating metabolism and activating soluble adenylyl cyclase in coronary vascular cells [PDF]

, 2017
M. Ahsan Siraj, Dhanwantee Mundil, Talat Afroze, Liu Ying, Michael B. Wheeler, G. Keller, Mansoor Husain   +6 more
openalex   +1 more source

Administration of Bicarbonate Protects Mitochondria, Rescues Retinal Ganglion Cells, and Ameliorates Visual Dysfunction Caused by Oxidative Stress

Antioxidants
Oxidative stress is a key factor causing mitochondrial dysfunction and retinal ganglion cell (RGC) death in glaucomatous neurodegeneration. The cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA) signaling pathway is involved in mitochondrial ...
Tonking Bastola, Guy A. Perkins, Viet Anh Nguyen Huu, Saeyeon Ju, Keun-Young Kim, Ziyao Shen, Dorota Skowronska-Krawczyk, Robert N. Weinreb, Won-Kyu Ju   +8 more
doaj   +1 more source

Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization. [PDF]

Mol Hum Reprod, 2021
Balbach M, Ghanem L, Rossetti T, Kaur N, Ritagliati C, Ferreira J, Krapf D, Puga Molina LC, Santi CM, Hansen JN, Wachten D, Fushimi M, Meinke PT, Buck J, Levin LR.   +14 more
europepmc   +1 more source

Discovery of TDI-10229: A Potent and Orally Bioavailable Inhibitor of Soluble Adenylyl Cyclase (sAC, ADCY10). [PDF]

ACS Med Chem Lett, 2021
Fushimi M, Buck H, Balbach M, Gorovyy A, Ferreira J, Rossetti T, Kaur N, Levin LR, Buck J, Quast J, van den Heuvel J, Steegborn C, Finkin-Groner E, Kargman S, Michino M, Foley MA, Miller M, Liverton NJ, Huggins DJ, Meinke PT.   +19 more
europepmc   +1 more source

Soluble Adenylyl Cyclase Mediates Nerve Growth Factor-induced Activation of Rap1 [PDF]

, 2006
A. Stessin, Jonathan H. Zippin, Margarita Kamenetsky, Kenneth C. Hess, Jochen Buck, Lonny R. Levin   +5 more
openalex   +1 more source

CRHR1-mediated Akt activation involves endocytosis and soluble adenylyl cyclase activity [PDF]

, 2022
Paula A. dos Santos Claro, Natalia G. Armando, Alejandra Attorresi, Karen E. Lindl, Micaela Silbermins, Carolina Inda, Susana Silberstein   +6 more
openalex   +1 more source

Effect of Soluble Adenylyl Cyclase (ADCY10) Inhibitors on the LH-Stimulated cAMP Synthesis in Mltc-1 Leydig Cell Line. [PDF]

Int J Mol Sci, 2021
Nguyen TMD, Filliatreau L, Klett D, Hai NV, Duong NT, Combarnous Y.   +5 more
europepmc   +1 more source

Phosphorylation of Spinophilin Modulates Its Interaction with Actin Filaments [PDF]

, 2003
Spinophilin is a protein phosphatase 1 (PP1)- and actin-binding protein that modulates excitatory synaptic transmission and dendritic spine morphology. We report that spinophilin is phosphorylated in vitro by protein kinase A (PKA).
Allen, Patrick B., Benfenati, Fabio, Greengard, Paul, Hsieh-Wilson, Linda C., Nairn, Angus C., Snyder, Gretchen L.   +5 more
core  

Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice. [PDF]

, 1998
Heart failure is accompanied by severely impaired beta-adrenergic receptor (betaAR) function, which includes loss of betaAR density and functional uncoupling of remaining receptors.
Chien, KR, Choi, DJ, Hunter, JJ, Iaccarino, G, Koch, WJ, Lefkowitz, RJ, Rockman, HA, Ross, J   +7 more
core  

Kinetic Properties of “Soluble” Adenylyl Cyclase [PDF]

Journal of Biological Chemistry, 2003
Tatiana N. Litvin, Margarita Kamenetsky, Alla Zarifyan, Jochen Buck, Lonny R. Levin   +4 more
openaire   +1 more source