Results 241 to 250 of about 19,003,286 (253)

Soluble Tim-3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression (VIR6P.1165)

The Journal of Immunology, 2015
Abstract Chronic HIV infection results in a loss of HIV-specific CD8+ T cell effector function, termed “exhaustion”, mediated, in part, by the co-inhibitory receptor T cell immunoglobulin mucin domain-3 (Tim-3). Like many other receptors, a soluble form of this protein has been described in human blood plasma.
Kiera Clayton, Matthew Douglas-Vail, A Rahman, Karyn Medcalf, Irene Xie, Glen Chew, Ravi Tandon, Marion Lanteri, Philip Norris, Steven Deeks, Lishomwa Ndhlovu, Mario Ostrowski   +11 more
openaire   +1 more source

Soluble immune checkpoints HVEM and TIM‐3 are prognostic biomarkers for outcome in classical Hodgkin lymphoma

Hematological Oncology, 2023
Ferdinandus, J., Cirillo, M., Bröckelmann, P.J., von Tresckow, Bastian, Klapper, W., Engert, A., Borchmann, P., Borchmann, S.   +7 more
openaire   +2 more sources

Serum soluble TIM-3 levels are increased in patients with diffuse cutaneous systemic sclerosis

Journal of Dermatological Science, 2017
Miki Chiba, Koichi Yanaba, Mitsuha Hayashi, Yuki Yoshihara, Hidemi Nakagawa   +4 more
openaire   +1 more source

Modulation of the Gal-9/TIM-3 Immune Checkpoint with α-Lactose. Does Anomery of Lactose Matter?

Cancers, 2021
Xavier Thuru, Christian Bailly, Bruno Quesnel   +2 more
exaly  

490P Metastatic breast cancer is associated with increased levels of soluble forms of TIM-3 and LAG-3 and decreased levels of soluble forms of GITR, GITR-L, CD27, CD28, CD40, CD86, ICOS, PD-L1, CTLA-4 and BTLA

Annals of Oncology, 2023
T. Smit, B.L. Rapoport, H. Steel, L. Heyman, C-A. Benn, R. Anderson   +5 more
openaire   +1 more source

Roles and correlations of TIM-3 and LAG-3 with cytokines and chemokines in alcoholic liver disease

Clinica Chimica Acta, 2023
Ailyn Fadriquela, Cheolsu Kim, Jong-Han Lee   +2 more
exaly  

Enhancement of SIV-specific cell mediated immune responses by co-administration of soluble PD-1 and Tim-3 as molecular adjuvants in mice

Human Vaccines and Immunotherapeutics, 2014
Liqiang Feng, Caijun Sun
exaly  

Soluble T cell immunoglobulin and mucin domain (TIM)-1 and -4 generated by A Disintegrin And Metalloprotease (ADAM)-10 and -17 bind to phosphatidylserine

Biochimica Et Biophysica Acta - Molecular Cell Research, 2014
Jürgen Scheller, Stefan Rose-John, Christoph Garbers   +2 more
exaly  

TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer

Cancer Cell, 2018
Hope Rugo, Matthew Krummel, Alvaro de Mingo Pulido   +2 more
exaly  

A head-to-head comparison of soluble dietary fibers on microbiota composition and short-chain fatty acid production using the in vitro TIM-2 system

Carbohydrate Polymers
Arquimedes Paixao de Santana-Filho, Daisy Jonkers, John Penders   +2 more
exaly