Results 11 to 20 of about 41,164 (267)

Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form

open access: yesHaematologica, 2015
Transferrin receptor-2 is a transmembrane protein whose expression is restricted to hepatocytes and erythroid cells. Transferrin receptor-2 has a regulatory function in iron homeostasis, since its inactivation causes systemic iron overload.
Alessia Pagani   +9 more
doaj   +1 more source

Cancer targeting with biomolecules: a comparative study of photodynamic therapy efficacy using antibody or lectin conjugated phthalocyanine-PEG gold nanoparticles [PDF]

open access: yes, 2015
The functionalisation of therapeutic nanoparticle constructs with cancer-specific biomolecules can enable selective tumour accumulation and targeted treatment. Water soluble gold nanoparticles (ca.
Allen   +49 more
core   +1 more source

The trypanosomal transferrin receptor of trypanosoma brucei : a review [PDF]

open access: yes, 2019
Iron is an essential element for life. Its uptake and utility requires a careful balancing with its toxic capacity, with mammals evolving a safe and bio-viable means of its transport and storage. This transport and storage is also utilized as part of the
Kariuki, Christopher K.   +2 more
core   +2 more sources

Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells [PDF]

open access: yes, 2005
Type 2 hereditary hemochromatosis (HH) or juvenile hemochromatosis is an early onset, genetically heterogeneous, autosomal recessive disorder of iron overload.
Bjorkman, Pamela J.   +4 more
core   +1 more source

Soluble serum transferrin receptor and transferrin receptor‐ferritin index in anemia of chronic kidney disease [PDF]

open access: yesDialysis & Transplantation, 2006
AbstractBackgroundThe aim of this study was to assess the value of the soluble serum transferrin receptor (sTfR) and the transferrin receptor‐ferritin index (sTfR/logF) as new markers of iron status in patients with anemia of chronic kidney disease (ACKD) both treated and not treated with recombinant human erythropoietin (rHuEPO) therapy.Materials and ...
Topić, Elizabeta   +3 more
openaire   +3 more sources

Non-invasive in vivo imaging of near infrared-labeled transferrin in breast cancer cells and tumors using fluorescence lifetime FRET. [PDF]

open access: yesPLoS ONE, 2013
The conjugation of anti-cancer drugs to endogenous ligands has proven to be an effective strategy to enhance their pharmacological selectivity and delivery towards neoplasic tissues.
Ken Abe   +4 more
doaj   +1 more source

Physiological and performance effects of live high train low altitude training for elite endurance athletes: A narrative review

open access: yesCurrent Research in Physiology, 2023
Altitude training has become an important training application for athletes due its potential for altering physiology and enhancing performance. This practice is commonly used by athletes, with a popular choice being the live high - train low approach ...
G. Bonato, S.P.J Goodman, Lathlean Tjh
doaj   +1 more source

Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery. [PDF]

open access: yes, 2012
In the forthcoming era of cancer gene therapy, efforts will be devoted to the development of new efficient and non-toxic gene delivery vectors. In this regard, the use of Fmoc/Boc-protected oligo(ethane amino)acids as building blocks for solid-phase ...
Akinc   +78 more
core   +3 more sources

NILAI RUJUKAN SOLUBLE TRANSFERRIN RECEPTOR (sTfR) {(Soluble Transferrin Receptor Refence Value (sTfR)}

open access: yesINDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2018
Iron in plasma is carried by transferrin delivered to cells through the interaction with a specific membrane receptor, namelytransferrin receptor. The soluble transferrin receptor (sTfR) is a transferrin receptor monomer which lost its first 100 amino acids, andcirculates in the form of transferrin and its receptor complex.
Anggraini Iriani   +2 more
openaire   +2 more sources

Some aspects of the transport system of iron metabolism depending on the degree of iron overload syndrome in children with chronic hepatitis B

open access: yesДетские инфекции (Москва), 2019
Objective: to study the status of markers of the transport system of iron metabolism and the marker profile of HBV infection, depending on the degree of iron overload syndrome in children with chronic hepatitis B.The object of the study were 1 85 ...
F. I. Inoyatova   +6 more
doaj   +1 more source

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