Results 11 to 20 of about 41,164 (267)
Transferrin receptor-2 is a transmembrane protein whose expression is restricted to hepatocytes and erythroid cells. Transferrin receptor-2 has a regulatory function in iron homeostasis, since its inactivation causes systemic iron overload.
Alessia Pagani +9 more
doaj +1 more source
Cancer targeting with biomolecules: a comparative study of photodynamic therapy efficacy using antibody or lectin conjugated phthalocyanine-PEG gold nanoparticles [PDF]
The functionalisation of therapeutic nanoparticle constructs with cancer-specific biomolecules can enable selective tumour accumulation and targeted treatment. Water soluble gold nanoparticles (ca.
Allen +49 more
core +1 more source
The trypanosomal transferrin receptor of trypanosoma brucei : a review [PDF]
Iron is an essential element for life. Its uptake and utility requires a careful balancing with its toxic capacity, with mammals evolving a safe and bio-viable means of its transport and storage. This transport and storage is also utilized as part of the
Kariuki, Christopher K. +2 more
core +2 more sources
Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells [PDF]
Type 2 hereditary hemochromatosis (HH) or juvenile hemochromatosis is an early onset, genetically heterogeneous, autosomal recessive disorder of iron overload.
Bjorkman, Pamela J. +4 more
core +1 more source
Soluble serum transferrin receptor and transferrin receptor‐ferritin index in anemia of chronic kidney disease [PDF]
AbstractBackgroundThe aim of this study was to assess the value of the soluble serum transferrin receptor (sTfR) and the transferrin receptor‐ferritin index (sTfR/logF) as new markers of iron status in patients with anemia of chronic kidney disease (ACKD) both treated and not treated with recombinant human erythropoietin (rHuEPO) therapy.Materials and ...
Topić, Elizabeta +3 more
openaire +3 more sources
Non-invasive in vivo imaging of near infrared-labeled transferrin in breast cancer cells and tumors using fluorescence lifetime FRET. [PDF]
The conjugation of anti-cancer drugs to endogenous ligands has proven to be an effective strategy to enhance their pharmacological selectivity and delivery towards neoplasic tissues.
Ken Abe +4 more
doaj +1 more source
Altitude training has become an important training application for athletes due its potential for altering physiology and enhancing performance. This practice is commonly used by athletes, with a popular choice being the live high - train low approach ...
G. Bonato, S.P.J Goodman, Lathlean Tjh
doaj +1 more source
Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery. [PDF]
In the forthcoming era of cancer gene therapy, efforts will be devoted to the development of new efficient and non-toxic gene delivery vectors. In this regard, the use of Fmoc/Boc-protected oligo(ethane amino)acids as building blocks for solid-phase ...
Akinc +78 more
core +3 more sources
Iron in plasma is carried by transferrin delivered to cells through the interaction with a specific membrane receptor, namelytransferrin receptor. The soluble transferrin receptor (sTfR) is a transferrin receptor monomer which lost its first 100 amino acids, andcirculates in the form of transferrin and its receptor complex.
Anggraini Iriani +2 more
openaire +2 more sources
Objective: to study the status of markers of the transport system of iron metabolism and the marker profile of HBV infection, depending on the degree of iron overload syndrome in children with chronic hepatitis B.The object of the study were 1 85 ...
F. I. Inoyatova +6 more
doaj +1 more source

