Results 81 to 90 of about 41,164 (267)

Iron Deficiency and Blood Donation: Links, Risks and Management

Journal of Blood Medicine, 2022
Elpis Mantadakis,1 Paraskevi Panagopoulou,2 Eftychia Kontekaki,3 Zoe Bezirgiannidou,4 Georges Martinis3 1Department of Pediatrics, Hematology/ Oncology Unit, University General Hospital of Alexandroupolis, Thrace, Greece; 2Department of Pediatrics ...
Mantadakis E, Panagopoulou P, Kontekaki E, Bezirgiannidou Z, Martinis G   +4 more
doaj  

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

Advanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du, Dhanunjay Mukhi, Lingzhi Li, Chenyu Li, Siyu Pan, Bernhard Dumoulin, Eunji Ha, Lakshmi P Kolligundla, Yanjuan Hou, Jonathan Levinsohn, Chaelin Kang, Konstantin Adrian Klötzer, Junnan Wu, Samer Mohandes, Kathryn E Wellen, Katalin Susztak   +15 more
wiley   +1 more source

Iron Status and Associated Malaria Risk Among African Children. [PDF]

, 2018
BACKGROUND: It remains unclear whether improving iron status increases malaria risk, and few studies have looked at the effect of host iron status on subsequent malaria infection.
Atkinson, Sarah H, Bejon, Philip, Elliott, Alison M, Hill, Adrian VS, Kimita, Wandia, Lule, Swaib A, Macharia, Alex W, Mentzer, Alexander J, Morovat, Alireza, Muriuki, John Muthii, Ndungu, Francis M, Webb, Emily L, Williams, Thomas N   +12 more
core   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Transition metal ions at the crossroads of mucosal immunity and microbial pathogenesis. [PDF]

, 2014
Transition metal ions are essential micronutrients for all living organisms. In mammals, these ions are often protein-bound and sequestered within cells, limiting their availability to microbes. Moreover, in response to infection, mammalian hosts further
Diaz-Ochoa, Vladimir E, Jellbauer, Stefan, Klaus, Suzi, Raffatellu, Manuela   +3 more
core   +2 more sources

Soluble transferrin receptor and soluble transferrin receptor/log ferritin index in coronavirus disease 2019

The Egyptian Journal of Haematology
Background The coronavirus disease 2019 (COVID-19) pandemic impacted a huge number of people worldwide, with high morbidity and mortality. Consistent findings indicated a potential role of iron parameters, hyperferritinemia, and ferroptosis in the pathogenesis of multiorgan failure, and it might serve as a new treatment target.
Abdalla E. Abdalla, Saad A. Doha, Soliman M. Nashaat, Abdel-Hamid S. Alaa El-Din, Saad A. Mohammed, Nashaat H. Hebat-Allah   +5 more
openaire   +1 more source

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

Advanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer, Steffen Honrath, Jonas Kurmann, Alexander Klipp, Finn Brigger, Jean‐Christophe Leroux   +5 more
wiley   +1 more source

Assessment of Regression Models for Adjustment of Iron Status Biomarkers for Inflammation in Children with Moderate Acute Malnutrition in Burkina Faso. [PDF]

, 2016
BACKGROUND: Biomarkers of iron status are affected by inflammation. In order to interpret them in individuals with inflammation, the use of correction factors (CFs) has been proposed.
Christensen, Vibeke Brix, Cichon, Bernardette, Fabiansen, Christian, Filteau, Suzanne, Friis, Henrik, Kæstel, Pernille, Ritz, Christian   +6 more
core   +3 more sources

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Soluble transferrin receptors in malaria.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2012
To determine the concentration of soluble transferrin receptors (sTfR) in patients with malaria.Cross-sectional, analytical study.Baqai Institute of Haematology, Baqai Medical University, Karachi, from December 2009 to April 2010.Twenty samples from normal male and female subjects each were drawn for establishing the reference range while 38 from ...
Muhammad, Saboor, , Moinuddin, Muhammad Abdul, Razzaq, Naeem, Tahir   +3 more
openaire   +1 more source