Results 71 to 80 of about 1,044,480 (214)

The impact of supplementation with pomegranate fruit (Punica granatum L.) juice on selected antioxidant parameters and markers of iron metabolism in rowers

Journal of the International Society of Sports Nutrition, 2018
Background The aim of this study was to analyse the effect of pomegranate juice (POM) supplementation on the levels of selected pro-inflammatory cytokines, hepcidin and markers of iron metabolism in well-trained rowers.
A. Urbaniak, P. Basta, K. Ast, A. Wołoszyn, J. Kuriańska – Wołoszyn, Ewa Latour, A. Skarpańska – Stejnborn   +6 more
doaj   +1 more source

Subclinical iron deficiency is a strong predictor of bacterial vaginosis in early pregnancy

BMC Infectious Diseases, 2005
Background Bacterial vaginosis (BV) is the single most common vaginal infection in women of childbearing age and associated with a sizeable infectious disease burden among both non-pregnant and pregnant women, including a significantly elevated risk of ...
Claeys Geert, Blot Stijn, Roelens Kristien, Delanghe Joris, Verstraelen Hans, Temmerman Marleen   +5 more
doaj   +1 more source

Obesity‐Related Inflammation Masks Iron Deficiency in US Women

American Journal of Hematology, EarlyView.
Sixtus Aguree, Sai Chakrri Tadikonda
wiley   +1 more source

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

Medicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo, Kaeun Chae, Jueun Lee, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Aptamer–Based Targeted Protein Degradation: Mechanistic Principles, Delivery Strategies, and Translational Opportunities

Medicinal Research Reviews, EarlyView.
ABSTRACT Targeted elimination of pathogenic proteins remains a fundamental challenge in therapeutic intervention, particularly for proteins considered “undruggable” by conventional inhibition‐based approaches. Aptamer–based targeted protein degradation (TPD) has emerged as a versatile strategy that leverages the high specificity, structural ...
Ambrin Malik, Suyeon Son, Jaesung Lee, Ki Soo Park   +3 more
wiley   +1 more source

Optimal blood transfusion therapy in haemoglobinopathies

Thalassemia Reports, 2018
For reasons of time, this short talk will be confined to the optimal frequency, timing, indications and dosing of blood transfusion. Blood transfusion protocols in thalassaemia syndromes are more widely agreed (1) than for sickle disorders but questions ...
John Porter
doaj   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

Pathogenetic aspects of the influence of gliflozins on erythropoiesis and iron metabolism in patients with chronic heart failure

Лечащий Врач
Background. Sodium glucose cotransporter type 2 (SGLT2) inhibitors, established over the past decade, including dapagliflozin, empagliflozin, and canagliflozin, have demonstrated significant reductions in hospitalization and mortality in patients with ...
R. A. Khachaturyan, A. E. Karavozova, L. D. Khidirova   +2 more
doaj   +1 more source

Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy

Phytotherapy Research, EarlyView.
This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi, LuLu Zhang, Lan Yan, Qi Geng, Li Li, Xiaojuan He, Ning Zhao, Yong Tan, Xiaomeng Zhang, Cheng Lu   +9 more
wiley   +1 more source

Iron parameters analysis in dogs with myxomatous mitral valve disease

BMC Veterinary Research
Background Myxomatous mitral valve disease (MMVD) is the most common acquired cardiovascular disease in small breed dogs. In contrast to human patients with heart failure (HF), iron deficiency (ID) prevalence in dogs with MMVD is weakly known.
Ewa Kumiega, Kamil A Kobak, Agnieszka Noszczyk-Nowak, Monika Kasztura   +3 more
doaj   +1 more source