Results 71 to 80 of about 41,164 (267)

THE ROLE OF SERUM TRANSFERRIN RECEPTORS MEASUREMENT

open access: yesZdravniški Vestnik, 2004
Background. The transferrin receptors are transmembrane proteins. They have a critical role in iron metabolism by controlling the flow of transferrin iron into body cells.
Bernarda Vogrin   +4 more
doaj  

Iron Profile of Sickle Cell Disease Patients in Aminu Kano Teaching Hospital, Kano, Nigeria

open access: yesNigerian Journal of Medicine
Background: Sickle cell disease (SCD) is an inherited chronic haemolytic disorder that is characterised by chronic anaemia and recurrent body pains, with Nigeria accounting for the highest burden globally.
Awwal Musa Borodo   +5 more
doaj   +1 more source

トランスフェリンを介する鉄の細胞内取り込み機序 ―特に肝細胞への取り込みにおける内皮細胞の関与について― [PDF]

open access: yes, 1988
Transferrin (Tf) is thought to play a pivotal role in iron metabolism of various kinds of cells. Tf has specific receptors on the surface of the cells that require iron.
Harada, Hideo   +6 more
core   +1 more source

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

open access: yesAdvanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti   +13 more
wiley   +1 more source

Physiologic cold shock of Moraxella catarrhalis affects the expression of genes involved in the iron acquisition, serum resistance and immune evasion

open access: yesBMC Microbiology, 2011
Background Moraxella catarrhalis, a major nasopharyngeal pathogen of the human respiratory tract, is exposed to rapid downshifts of environmental temperature when humans breathe cold air.
Schaller André   +3 more
doaj   +1 more source

Soluble transferrin receptor and soluble transferrin receptor/log ferritin index in diagnosis of iron deficiency anemia in pediatric inflammatory bowel disease [PDF]

open access: yesDigestive and Liver Disease, 2019
There is no single reliable marker of iron homeostasis in inflammatory bowel disease.To determine diagnostic usefulness of soluble transferrin receptor and soluble transferrin receptor/log ferritin index in iron deficiency anemia in children with inflammatory bowel disease.We assessed soluble transferrin receptor in serum and calculated soluble ...
Paulina Krawiec   +1 more
openaire   +3 more sources

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

open access: yesAdvanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel   +15 more
wiley   +1 more source

IRON DEFICIENCY ANEMIA AND ANEMIA OF CHRONIC DISEASES: SOME ASPECTS OF THE PATHOGENESIS AND PROSPECTS OF DIFFERENTIAL DIAGNOSIS

open access: yesМедицина в Кузбассе, 2019
Objective – to evaluate the information content of modern methods for studying iron metabolism in the algorithm for the differential diagnosis of hypochromic anemias. Materials and methods. A total of 296 women aged 16 to 60 years with an anemic syndrome
Сатеник Аршавиловна Клочкова-Абельянц   +1 more
doaj  

Iron status in children with acute COVID-19 and paediatric inflammatory multisystem syndrome during infection and after recovery

open access: yesEgyptian Pediatric Association Gazette
Background COVID-19 has significant effects on organ function, particularly on lung function and iron metabolism. Studies have shown increased levels of ferritin, an iron storage protein, in COVID-19 patients, indicating potential changes in iron ...
Mai S. El-Meshad   +4 more
doaj   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong   +8 more
wiley   +1 more source

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