Results 41 to 50 of about 1,856,875 (191)

Evaluation of Soluble Urokinase Plasminogen Activator Receptor in COVID-19 Patients. [PDF]

J Clin Med
Background/Objectives: This retrospective study analyzed soluble urokinase plasminogen activator receptor (suPAR) plasma levels alongside routine inflammatory markers, including the neutrophil-to-lymphocyte count ratio, C-reactive protein (CRP), interleukin-6 (IL-6), procalcitonin (PCT), and D-dimers in COVID-19 patients hospitalized during the Omicron
Arientová S, Matúšková K, Bartoš O, Beran O, Holub M.   +4 more
europepmc   +3 more sources

Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]

, 2003
Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R., Wosikowski, K., Probst, C., Sander, C. A., Degitz, K., Schuh, T., Flaig, M. J., Braungart, E., Douwes, K., Magdolen, V., C.A. Sander, C. Probst, K. Wosikowski, K. Degitz, T. Schuh, R. Besch, E. Braungart, V. Magdolen, M.J. Flaig, K. Douwes   +19 more
core   +2 more sources

Transcriptional regulation of the urokinase receptor (u-PAR) - A central molecule of invasion and metastasis [PDF]

, 2003
The phenomenon of tumor-associated proteolysis has been acknowledged as a decisive step in the progression of cancer. This short review focuses on the urokinase receptor (u-PAR), a central molecule involved in tumor-associated invasion and metastasis ...
Fuchs, T., Allgayer, H.
core   +1 more source

The role of soluble urokinase plasminogen activator receptor (suPAR) in patients with cancer: a review of the current literature [PDF]

Medicinski Glasnik, 2022
Aim Several biomarkers are currently used as diagnostic and prognostic tools in patients with cancer. Soluble urokinase plasminogen activator receptor (suPAR) is elevated in acute and chronic inflammatory procedures and several observational studies ...
Themistoklis Paraskevas, Francesk Mulita, Christos Michailides, Georgios-Ioannis Verras, Elias Liolis, Eleousa Oikonomou, Ioannis Perdikaris, Konstantinos Bouchagier, Ioannis Panagiotopoulos, Dimitrios-Ioannis Kasartzian, Dimitrios Filis, Levan Tchabashvili, Despoina Spyropoulou, Dimitrios Velissaris   +13 more
doaj   +1 more source

Soluble Urokinase Plasminogen Activator Receptor (suPAR) in Autoimmune Rheumatic and Non Rheumatic Diseases. [PDF]

J Pers Med, 2023
The soluble urokinase plasminogen activator receptor (suPAR) is the bioactive form of uPAR, a membrane-bound glycoprotein, and it is primarily expressed on the surface of immunologically active cells.
Manfredi M, Van Hoovels L, Benucci M, De Luca R, Coccia C, Bernardini P, Russo E, Amedei A, Guiducci S, Grossi V, Bossuyt X, Perricone C, Infantino M.   +12 more
europepmc   +2 more sources

Circulating Soluble Urokinase-Type Plasminogen Activator Receptor in Obstructive Sleep Apnoea

Medicina, 2020
Background and Objectives: Obstructive sleep apnoea (OSA) is associated with heightened systemic inflammation and a hypercoagulation state. Soluble urokinase-type plasminogen activator receptor (suPAR) plays a role in fibrinolysis and systemic ...
Renata Marietta Bocskei, Martina Meszaros, Adam Domonkos Tarnoki, David Laszlo Tarnoki, Laszlo Kunos, Zsofia Lazar, Andras Bikov   +6 more
doaj   +1 more source

Soluble urokinase plasminogen activator receptor and survival in elective cardiac surgery

European Journal of Clinical Investigation, 2023
AbstractBackgroundThe study investigated the prognostic value of soluble urokinase plasminogen activator receptor (suPAR) in patients undergoing cardiac surgery and calculated a simplified biomarker score comprising suPAR, N‐terminal pro B‐type natriuretic peptide (NT‐proBNP) and age.Methods and ResultsBiomarkers were assessed in a cohort of 478 ...
Lorenz Koller, Eva Steinacher, Felix Hofer, Andreas Hammer, Niema Kazem, Guenther Laufer, Tatjana Fleck, Barbara Steinlechner, Johann Wojta, Bernhard Richter, Christian Hengstenberg, Patrick Sulzgruber, Alexander Niessner   +12 more
openaire   +2 more sources

Serum Soluble Urokinase Plasminogen Activator Receptor Levels in Resistant Hypertension

Turkish Journal of Nephrology
Background: Although the precise pathogenetic mechanisms remain incompletely elucidated, hypertension is characterized by endothelial damage and inflammation. The soluble urokinase plasminogen activator receptor (suPAR) is an inflammatory biomarker that
Nergiz Bayrakcı, Gülsüm Özkan, Sonat Pınar Kara, Ahsen Yılmaz, Aliye Çelikkol   +4 more
doaj   +3 more sources

The study of molecular markers for the progression of Barrett's Oesophagus to adenocarcinoma to identify markers that can be used as diagnostic tools. [PDF]

, 2002
Barrett's oesophagus is a complication of gastro-oesophageal reflux disease and is the single most important predisposing factor for the development of adenocarcinoma of the oesophagus.
Cadd, Verity Anne
core   +4 more sources

PLAUR (plasminogen activator, urokinase receptor) [PDF]

, 2010
Review on PLAUR (plasminogen activator, urokinase receptor), with data on DNA, on the protein encoded, and where the gene is ...
B Jacobsen, M Ploug, M Illemann, Jacobsen, B, Ploug, M, Illemann, M   +5 more
core   +1 more source