Results 71 to 80 of about 2,673 (255)

A solvable system of difference equations [PDF]

open access: yes, 2020
Summary: In this paper, we show that the system of difference equations \[x_n={\frac{ay^p_{n-1}+b(x_{n-2}y_{n-1})^{p-1}}{cy_{n-1}+dx^{p-1}_{n-2}}},\ y_n={\frac{{\alpha}x^p_{n-1}+{\beta}(y_{n-2}x_{n-1})^{p-1}}{{\gamma}x_{n-1}+{\delta}y^{p-1}_{n-2}}}, \] \(n\in \mathbb{N}_0\) where the parameters \(a, b, c, d, \alpha, \beta, \gamma, \delta, p\) and the ...
Taskara, Necati.   +3 more
openaire   +2 more sources

Solvability and different solutions of the operator equation $$XAX=BX$$

open access: yesAnnals of Functional Analysis, 2022
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Inversive Difference Modules and Solvability of Systems of Linear Difference Equations

open access: yesRocky Mountain Journal of Mathematics, 2007
The author studies homological properties of inversive difference modules and applies them to the problem of solvability of a system of linear difference equations over a difference field. He proves the existence of Grothendieck's spectral sequence for the functor Ext in the category of inversive difference modules.
openaire   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Hydrodynamics of local excitations after an interaction quench in 1D cold atomic gases

open access: yesNew Journal of Physics, 2016
We discuss the hydrodynamic approach to the study of the time evolution—induced by a quench—of local excitations in one dimension. We focus on interaction quenches: the considered protocol consists of creating a stable localized excitation propagating ...
Fabio Franchini   +2 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

The theory behind solvability of some difference equations and systems

open access: yesJournal of Inequalities and Applications
Quite recently in the paper ‘Qualitative behavior of higher-order rational difference systems: positivity, asymptotic behavior, and periodicity’ (J. Inequal. Appl.
Stevo Stević
doaj   +1 more source

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