Results 71 to 80 of about 11,944 (302)
Periodic Solutions of a Many-Rotator Problem in the Plane. II. Analysis of Various Motions
, 2003 Various solutions are displayed and analyzed (both analytically and numerically) of a recently-introduced many-body problem in the plane which includes both integrable and nonintegrable cases (depending on the values of the coupling constants); in ...
Calogero, F +6 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
On exactly solvable ghost-ridden systems
, 2020 International audienceWe discuss exactly solvable systems involving integrals of motion with higher powers of momenta. If one of these integrals is chosen for the Hamiltonian, we obtain a higher-derivative system involving ghosts, i.e.
Smilga, A.V., Smilga, Andrei
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Models for Quadratic Algebras Associated with Second Order Superintegrable Systems in 2D
, 2008 There are 13 equivalence classes of 2D second order quantum and classical superintegrable systems with nontrivial potential, each associated with a quadratic algebra of hidden symmetries.
Willard Miller Jr. +5 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Scheduling distributed computations in non-deterministic systems
Научно-технический вестник информационных технологий, механики и оптикиComputation scheduling is very important in the design of distributed information processing and control systems. Effective scheduling algorithms allow developer to find technical solutions that are adequate to the existing constraints.
N. V. Kolesov +3 more
doaj +1 more source
Predicting EHL film thickness parameters by machine learning approaches
Friction, 2022 Non-dimensional similarity groups and analytically solvable proximity equations can be used to estimate integral fluid film parameters of elastohydrodynamically lubricated (EHL) contacts.
Max Marian +5 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source