Results 61 to 70 of about 4,193,000 (282)

Crystal structure of the 4 + 2 cycloadduct of photooxidized anthracene and C60 fullerene

Acta Crystallographica Section E, 2014
The structure of the title compound, 5,6-[(1R,10S)-2,9-dioxatricyclo[8.6.03,8.011,16]hexadecane-1,10-diyl]-(C60–Ih)[5,6]fullerene methanedithione 0.1-solvate, C74H10O2·0.1CS2, has tetragonal (P42/n) symmetry at 100 K. It has a unique eight-membered ring,
Gábor Bortel, Éva Kováts, Gábor Oszlányi, Sándor Pekker   +3 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Triazidotris[μ-2-(2-pyridyl)ethanolato]dicobalt(II) acetonitrile monosolvate

Acta Crystallographica Section E, 2010
In the title compound, [Co2(C7H8NO)3(N3)3]·CH3CN, the two CoII ions in the dinuclear complex have different coordination environments, both in a distorted octahedral geometry.
Dacheng Li, Lei Lv, Shizheng Liu, Jie Yang   +3 more
doaj   +1 more source

Role of Trapped and Solvated Electrons in Ps Formation

Acta Physica Polonica A, 2005
Role of trapped and solvated electrons in Ps formation is discussed. Combination of thermalized positron with such electrons is possible from the viewpoint of the energy balance and may results in Ps formation. This process proceeds during all e + lifetime in matter.
S.V. Stepanov, V.M. Byakov, C. He, T. Hirade, K.V. Mikhin   +4 more
openaire   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Chlorothiazide dimethyl sulfoxide solvate

, 2007
Chlorothiazide forms a 1:1 solvate with dimethyl sulfoxide (systematic name: 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide dimethyl sulfoxide solvate), C7H6ClN3O4S2·C2H6OS.
Johnston, Andrea, Florence, Alastair J., Kennedy, Alan R., Fernandes, Philippe   +3 more
core   +3 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Solvation Energetic Costs of Cognate Binding Site Formation

Journal of Chemical Information and Modeling
Structural fluctuations of proteins can reveal alternate binding site conformations or cryptic pockets that may be exploited to discover novel, tightly bound chemical compounds. While significant effort has been dedicated to the exploration of protein conformational space, the thermodynamic role of solvation and how it is coupled to a protein's ...
Yeonji Ji, Vjay Molino, Steven Ramsey, Tom Kurtzman   +3 more
openaire   +4 more sources

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Solvate Prediction for Pharmaceutical Organic Molecules with Machine Learning

, 2019
Methods to predict crystallization behavior for active pharmaceutical ingredients (APIs) can serve as an important guide in small molecule pharmaceutical development.
Xiaorong He (2662138), Keith Horspool (3992564), Dongyue Xin (1316298), Nina C. Gonnella (1479187)   +3 more
core   +2 more sources