Results 81 to 90 of about 5,622 (240)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
We present an investigation of solvate formation of isonicotinamide (INA) with linear monocarboxylic acids and several other solvents and characterization of the obtained solvates, their structure, and structural similarity with INA polymorphs and ...
Anatoly Mishnev (1556635) +4 more
core +1 more source
Over one hundred solvates of sulfathiazole
, 2001 The sulfadrug sulfathiazole forms an extensive family of solvates and adducts, the crystal structures of which show a large variety of hydrogen-bonded ...
Threlfall, Terence L. +11 more
core +1 more source
Crystal structures of two solvates of (18-crown-6)potassium acetate
Acta Crystallographica Section E: Crystallographic Communications, 2016 The crystal and molecular strutures of two solvated forms of [K(18c6)]OAc (18c6 = 18-crown-6 = 1,4,7,10,13,16-hexaoxacyclooctadecane and OAc = acetate) were determined by single-crystal X-ray diffraction, namely (acetato-κ2O,O′)(1,4,7,10,13,16 ...
Phil Liebing +3 more
doaj +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Isostructurality among five solvates of phenylbutazone
This work describes the crystal structures of phenylbutazone 2:1 solvates with benzene, cyclohexane, 1,4-dioxane, tetrahydrofuran, tetrachloromethane, and chloroform. These solvates are isostructural, with the exception of the chloroform solvate.
Datta S +5 more
core +4 more sources
CrystalsCarbon dioxide (CO2) has a wide range of uses such as food additives and raw materials for synthetic chemicals, while its application in the solid-state transformation of pharmaceutical crystals is rare.
Lixin Hou +3 more
doaj +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2019 Charge-assisted hydrogen bonding plays a significant role in the crystal structures of solvates of ionic compounds, especially when the cation or cations are primary ammonium salts.
Dean H. Johnston, Ikponmwosa Agho
doaj +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Vapor triggered fluorescent color changes among solvates of Emodin
, 2017 EM solvates' reversible vapochromic phenomena were fully studied to provide a new approach to find vapor sensitive MCL materials.
Meiqi Li +4 more
core +1 more source