Results 51 to 60 of about 4,684,020 (381)

Quantitative Market Risk Assessment for Insurance Companies

open access: yesФинансы: теория и практика, 2022
The business strategy, the underwriting policy, the investment strategy of insurance companies and some external factors influence their ability to meet liabilities.
E. V. Aldukhova
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

THE IMPACT OF TRANSITION FROM SOLVENCY I TO SOLVENCY II OVER THE PREMIUM RESERVES IN GENERAL INSURANCE [PDF]

open access: yesEconomica, 2020
One of the most important purposes of any insurance company is to be solvable. The technical reserve represents the main part of the obligations of an insurance company, thus the correct evaluation of this item is primordial.
Oleg VEREJAN, Victor CALDARE
doaj  

A review of the risk margin – Solvency II and beyond

open access: yesBritish Actuarial Journal, 2020
For life insurers in the United Kingdom (UK), the risk margin is one of the most controversial aspects of the Solvency II regime which came into force in 2016.
A. Pelkiewicz   +6 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Solventnost II in holistično obvladovanje tveganj

open access: yesEconomic and Business Review, 2017
The Solvency II Directive poses a major challenge to insurance companies, fundamentally changing the way they currently do business. In the study, we examined the qualitative requirements of the so-called second pillar, namely the role, importance and ...
Helena Bešter
doaj   +1 more source

Own Risk and Solvency Assessment Within the Solvency II Framework and its Interplay with the Quantitative Solvency Capital Requirements [PDF]

open access: yes, 2013
Pursuant to art. 45 of the Solvency II Framework Directive, all insurance undertakings will be obliged to conduct an “Own Risk and Solvency Assessment” (ORSA).
Gal, Jens, Gründl, Helmut
core  

The standard formula of Solvency II: a critical discussion

open access: yesEuropean Actuarial Journal, 2020
Establishing a standard formula (SF) for the regulation of European insurance companies is a Herculean task. It has to acknowledge very different business models and national peculiarities.
M. Scherer, Gerhard Stahl
semanticscholar   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

SOLVENCY II – THE NEW EU SOLVENCY REGIME ON THE INSURANCE MARKET [PDF]

open access: yesBuletin ştiinţific: Universitatea din Piteşti. Seria Ştiinţe Economice, 2012
The main causes that lead to insurer’s solvency issues such as the underwriting, investment or reinsurance deficiencies have remained the same over time. However, their incidence is increasing, as well as their complexity.
Emilia CLIPICI
doaj  

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