Results 61 to 70 of about 6,101,568 (282)
Assessment of the Stability of Insurance Companies: The Case of Baltic Non-Life Insurance Market
Economics and Business, 2018 The study gives an overview of the Baltic non-life insurance market. The purpose of the research is to summarise stability statistics on solvency ratios, risk profiles and capital surplus, which was contained in Solvency and Financial Condition reports ...
Zariņa Ilze +2 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
MODEL RISK AND DETERMINATION OF SOLVENCY CAPITAL IN THE SOLVENCY 2 FRAMEWORK [PDF]
This paper investigates the robustness of the Solvency Capital Requirement (SCR) when a log-normal reference model is slightly disturbed by the heaviness of its tail distribution.
Pierre-Emanuel Thérond +1 more
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Contabilidad y Negocios: Revista del Departamento Académico de Ciencias Administrativas, 2017 The new Solvency EU Directive II seeks to avoid repeating the uncertainty and destabilization situation produced in different sectors, especially in the financial, following a mispricing of assets.
Carmen Gloria Francisco Pérez +1 more
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Solvency II între IFRS 4 şi IFRS 17 [PDF]
Revista de Studii Financiare, 2020 Aplicarea începând din anul 2005 a Standardului de Raportare Financiară 4 – Contracte de asigurare (International Financial Reporting Standard 4-IFRS 4) a adus prin obiectivele sale, îmbunătătiri, clarificări, dar şi cerințe privind prezentările ...
Costin Andrei ISTRATE
doaj
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Rapporto Finale 2012 Osservatorio Solvency II
, 2013 L’Osservatorio Solvency II, realizzato da SDA Bocconi con la collaborazione di Capgemini, è un centro di elaborazione di idee e progetti dedicati all’impatto della regolamentazione prudenziale sul modello operativo delle Compagnie di assicurazione.
Simona Cosma +4 more
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